The Ethical Committee of Clinical Researches (Ethics Committee of İzmir Tepecik Training and Rese... more The Ethical Committee of Clinical Researches (Ethics Committee of İzmir Tepecik Training and Research Hospital) granted permission for this study with the decision number 2018/22-06-112. All procedures in this study involving human participants were performed in accordance with the 1964 Helsinki Declaration and its later amendments.
Objective: Surgical closure of ventricular septal defect is still the most common pediatric cardi... more Objective: Surgical closure of ventricular septal defect is still the most common pediatric cardiac surgical procedure. The aim of this study was to define the risk factors of the complications of ventricular septal defect surgery. Methods: We evaluated the preoperative, perioperative, and postoperative data from echocardiography reports, perfusion reports, and clinical, inpatient, and operative notes of all the patients. The following were the outcome variables for this study: in-hospital death; duration of mechanical ventilation in hours; duration of pediatric intensive care unit stay in days; and duration of hospital stay in days. Herein, we report our single pediatric cardiac center experience between October 2015 and October 2018. Results: A total of 108 patients underwent surgical ventricular septal defect closure during the study period. Prolonged pediatric intensive care unit stay, hospital stay and mechanical ventilation time was associated with younger age and low weight. The patients with genetic syndromes had statistically longer mechanical ventilation time (p < 0.001), pediatric intensive care unit stay (p < 0.001), and hospital stay (p = 0.002). Conclusion: Although genetic syndromes did not affect the complication rates, it affected the lengths of hospital and pediatric intensive care unit stays and mechanical ventilation duration. Young age and lower body weight was a risk factor of prolonged hospitalization, prolonged pediatric intensive care unit stay and prolonged mechanical ventilation. Therefore, these situations should be considered in the postoperative follow-up of patients with ventricular septal defect.
The aim of this study was to assess the surgical and follow-up outcomes in children who operated ... more The aim of this study was to assess the surgical and follow-up outcomes in children who operated for aberrant innominate artery. Methods: A total of 15 consecutive patients (12 males, 3 females; mean age 16.3 ± 19.0 months; range 3 months to 6 years) who underwent aortopexy between February 2018 and December 2021 were evaluated. Demographic data, preoperative and postoperative clinical status and postoperative outcomes were retrospectively analyzed. Results: The mean age at operation was 16.3 ± 19.0 months. The median weight was 8.3 kg (range, 7-14.5 kg).There was no complications at intraoperative period.The mean percent degree of tracheal stenosis was 0.68 ± 0.12. The median (range) MV duration, PICU stay, and ward stay of the patients were 2 hours (0-3 hours), 2.5 days (1-4 days), and 5 days (3-8 days), respectively. The mean patients' number of emergency service applications and hospitalization at the preoperative period was 6.2 ± 3.9 / 2.3 ± 1.6 and, at the postoperative period was 3.3 ± 2.2/ 0.9 ± 0.8. In comparison of the preoperative and postoperative service application number and hospitalization number, there was signi cant difference (p<0.005 and 0.006 respectively). No reoperation was required. There was no mortality. Conclusion: Aberrant innominate artery is rarely seen. These pathologies misdiagnosis with different reactive airways. Following the diagnosis, treatment can be achieved by surgery successfully.
Purpose: The aim of this study was to assess the surgical and follow-up outcomes in children who ... more Purpose: The aim of this study was to assess the surgical and follow-up outcomes in children who operated for aberrant innominate artery.Methods: A total of 15 consecutive patients (12 males, 3 females; mean age 16.3 ± 19.0 months; range 3 months to 6 years) who underwent aortopexy between February 2018 and December 2021 were evaluated. Demographic data, preoperative and postoperative clinical status and postoperative outcomes were retrospectively analyzed.Results: The mean age at operation was 16.3 ± 19.0 months. The median weight was 8.3 kg (range, 7–14.5 kg).There was no complications at intraoperative period.The mean percent degree of tracheal stenosis was 0.68 ± 0.12. The median (range) MV duration, PICU stay, and ward stay of the patients were 2 hours (0–3 hours), 2.5 days (1-4 days), and 5 days (3–8 days), respectively. The mean patients’ number of emergency service applications and hospitalization at the preoperative period was 6.2 ± 3.9 / 2.3 ± 1.6 and, at the postoperative...
Limbic encephalitis (LE) is an autoimmune neurological disorder associated with antibodies agains... more Limbic encephalitis (LE) is an autoimmune neurological disorder associated with antibodies against various antigens. 1,2 In childhood, most patients with autoimmune LE develop with antibodies against the N-methyl-D-aspartate (NMDA) glutamatergic receptor. 3 The most common type of autoimmune encephalitis in adults is leucine-rich glioma-inactivated protein 1 (LGI-1)-associated encephalitis. Leucine-rich glioma-inactivated proteins 1-4 take a serious role in synaptic maturation, transmission, and myelination. One of the new autoantigens in autoimmune encephalitis is LGI-1. 4 The median age of patients with LE associated with the LGI-1 antibody is 60 years. 5,6 The clinical presentation is variable, including severe short-term memory loss, psychiatric disturbances, and various types of seizures such as faciobrachial dystonic seizures (FBDS). 5,7 Frequent focal seizures were found in LGI-1-IgG-positive pediatric patients. 7 The condition may be complicated by severe hyponatremia in approximately 60% of cases. 8 Patients usually respond well to immunotherapy. 9 In this paper, we report the case of a 14-year-old girl who initially presented with ataxia and dysarthria, and was diagnosed with anti-LGI-1 LE. Case Report A 14-year-old, previously healthy girl was brought to the emergency department because of suspected dystonic seizure, ataxia, gait disturbance, and speech disorders. The additional symptoms reported by the parents were personality changes, visual hallucination, intermittent disorientation, balance disorders, hyperanxiety, intermittent headaches, and vomiting for approximately one month. On admission to the intensive care unit, a detailed neurological examination revealed dysarthria and 4/5 muscle strength in both the
What is already known on this topic? • Video laryncoscope is primarily recommended in cases where... more What is already known on this topic? • Video laryncoscope is primarily recommended in cases where a difficult airway is considered. • When endotracheal intubations of patients with normal airways were performed by experienced physicians, no difference was found between standard direct laryngoscopy and videolaryngoscopy in terms of intubation success. What this study adds on this topic? • There is a very limited number of studies in the literature among pediatricians, especially in pediatricians who have never used a video laryngoscope and have limited endotracheal intubation experience. • Residents in pediatrics with limited experience in endotracheal intubation use the videolaryngoscope more effectively than the standard direct laryngoscope after appropriate training.
Pulmonary venous stenosis (PVS) is a rare and progressive foetal disease (1). It is categorised i... more Pulmonary venous stenosis (PVS) is a rare and progressive foetal disease (1). It is categorised into congenital and acquired forms. Acquired PVS occurring due to atrial fibrillation (AF) ablation and after surgical correction of pulmonary venous return anomalies has been frequently described, but limited information is available regarding congenital PVS (2). The incidence of the disease is 0.4% in patients with congenital heart disease, whereas that of acquired PVS is 10%-15% after TAPVD correction and as high as 30%-40% after AF ablation (1,2) .
Turkish Journal of Pediatric Emergency and Intensive Care Medicine, 2018
6 months of follow-up. Decompressive craniectomy should be considered without delay in children w... more 6 months of follow-up. Decompressive craniectomy should be considered without delay in children with severe head trauma with neurological deterioration or intracranial pressure elevation refractory to medical treatment and in those with herniation.
IntroductionThere have been some significant changes regarding healthcare utilization during the ... more IntroductionThere have been some significant changes regarding healthcare utilization during the COVID-19 pandemic. Majority of the reports about the impact of the COVID-19 pandemic on diabetes care are from the first wave of the pandemic. We aim to evaluate the potential effects of the COVID-19 pandemic on the severity of diabetic ketoacidosis (DKA) and new onset Type 1 diabetes presenting with DKA, and also evaluate children with DKA and acute COVID-19 infection.MethodsThis is a retrospective multi-center study among 997 children and adolescents with type 1 diabetes who were admitted with DKA to 27 pediatric intensive care units in Turkey between the first year of pandemic and pre-pandemic year.ResultsThe percentage of children with new-onset Type 1 diabetes presenting with DKA was higher during the COVID-19 pandemic (p < 0.0001). The incidence of severe DKA was also higher during the COVID-19 pandemic (p < 0.0001) and also higher among children with new onset Type 1 diabete...
The Ethical Committee of Clinical Researches (Ethics Committee of İzmir Tepecik Training and Rese... more The Ethical Committee of Clinical Researches (Ethics Committee of İzmir Tepecik Training and Research Hospital) granted permission for this study with the decision number 2018/22-06-112. All procedures in this study involving human participants were performed in accordance with the 1964 Helsinki Declaration and its later amendments.
Objective: Surgical closure of ventricular septal defect is still the most common pediatric cardi... more Objective: Surgical closure of ventricular septal defect is still the most common pediatric cardiac surgical procedure. The aim of this study was to define the risk factors of the complications of ventricular septal defect surgery. Methods: We evaluated the preoperative, perioperative, and postoperative data from echocardiography reports, perfusion reports, and clinical, inpatient, and operative notes of all the patients. The following were the outcome variables for this study: in-hospital death; duration of mechanical ventilation in hours; duration of pediatric intensive care unit stay in days; and duration of hospital stay in days. Herein, we report our single pediatric cardiac center experience between October 2015 and October 2018. Results: A total of 108 patients underwent surgical ventricular septal defect closure during the study period. Prolonged pediatric intensive care unit stay, hospital stay and mechanical ventilation time was associated with younger age and low weight. The patients with genetic syndromes had statistically longer mechanical ventilation time (p < 0.001), pediatric intensive care unit stay (p < 0.001), and hospital stay (p = 0.002). Conclusion: Although genetic syndromes did not affect the complication rates, it affected the lengths of hospital and pediatric intensive care unit stays and mechanical ventilation duration. Young age and lower body weight was a risk factor of prolonged hospitalization, prolonged pediatric intensive care unit stay and prolonged mechanical ventilation. Therefore, these situations should be considered in the postoperative follow-up of patients with ventricular septal defect.
The aim of this study was to assess the surgical and follow-up outcomes in children who operated ... more The aim of this study was to assess the surgical and follow-up outcomes in children who operated for aberrant innominate artery. Methods: A total of 15 consecutive patients (12 males, 3 females; mean age 16.3 ± 19.0 months; range 3 months to 6 years) who underwent aortopexy between February 2018 and December 2021 were evaluated. Demographic data, preoperative and postoperative clinical status and postoperative outcomes were retrospectively analyzed. Results: The mean age at operation was 16.3 ± 19.0 months. The median weight was 8.3 kg (range, 7-14.5 kg).There was no complications at intraoperative period.The mean percent degree of tracheal stenosis was 0.68 ± 0.12. The median (range) MV duration, PICU stay, and ward stay of the patients were 2 hours (0-3 hours), 2.5 days (1-4 days), and 5 days (3-8 days), respectively. The mean patients' number of emergency service applications and hospitalization at the preoperative period was 6.2 ± 3.9 / 2.3 ± 1.6 and, at the postoperative period was 3.3 ± 2.2/ 0.9 ± 0.8. In comparison of the preoperative and postoperative service application number and hospitalization number, there was signi cant difference (p<0.005 and 0.006 respectively). No reoperation was required. There was no mortality. Conclusion: Aberrant innominate artery is rarely seen. These pathologies misdiagnosis with different reactive airways. Following the diagnosis, treatment can be achieved by surgery successfully.
Purpose: The aim of this study was to assess the surgical and follow-up outcomes in children who ... more Purpose: The aim of this study was to assess the surgical and follow-up outcomes in children who operated for aberrant innominate artery.Methods: A total of 15 consecutive patients (12 males, 3 females; mean age 16.3 ± 19.0 months; range 3 months to 6 years) who underwent aortopexy between February 2018 and December 2021 were evaluated. Demographic data, preoperative and postoperative clinical status and postoperative outcomes were retrospectively analyzed.Results: The mean age at operation was 16.3 ± 19.0 months. The median weight was 8.3 kg (range, 7–14.5 kg).There was no complications at intraoperative period.The mean percent degree of tracheal stenosis was 0.68 ± 0.12. The median (range) MV duration, PICU stay, and ward stay of the patients were 2 hours (0–3 hours), 2.5 days (1-4 days), and 5 days (3–8 days), respectively. The mean patients’ number of emergency service applications and hospitalization at the preoperative period was 6.2 ± 3.9 / 2.3 ± 1.6 and, at the postoperative...
Limbic encephalitis (LE) is an autoimmune neurological disorder associated with antibodies agains... more Limbic encephalitis (LE) is an autoimmune neurological disorder associated with antibodies against various antigens. 1,2 In childhood, most patients with autoimmune LE develop with antibodies against the N-methyl-D-aspartate (NMDA) glutamatergic receptor. 3 The most common type of autoimmune encephalitis in adults is leucine-rich glioma-inactivated protein 1 (LGI-1)-associated encephalitis. Leucine-rich glioma-inactivated proteins 1-4 take a serious role in synaptic maturation, transmission, and myelination. One of the new autoantigens in autoimmune encephalitis is LGI-1. 4 The median age of patients with LE associated with the LGI-1 antibody is 60 years. 5,6 The clinical presentation is variable, including severe short-term memory loss, psychiatric disturbances, and various types of seizures such as faciobrachial dystonic seizures (FBDS). 5,7 Frequent focal seizures were found in LGI-1-IgG-positive pediatric patients. 7 The condition may be complicated by severe hyponatremia in approximately 60% of cases. 8 Patients usually respond well to immunotherapy. 9 In this paper, we report the case of a 14-year-old girl who initially presented with ataxia and dysarthria, and was diagnosed with anti-LGI-1 LE. Case Report A 14-year-old, previously healthy girl was brought to the emergency department because of suspected dystonic seizure, ataxia, gait disturbance, and speech disorders. The additional symptoms reported by the parents were personality changes, visual hallucination, intermittent disorientation, balance disorders, hyperanxiety, intermittent headaches, and vomiting for approximately one month. On admission to the intensive care unit, a detailed neurological examination revealed dysarthria and 4/5 muscle strength in both the
What is already known on this topic? • Video laryncoscope is primarily recommended in cases where... more What is already known on this topic? • Video laryncoscope is primarily recommended in cases where a difficult airway is considered. • When endotracheal intubations of patients with normal airways were performed by experienced physicians, no difference was found between standard direct laryngoscopy and videolaryngoscopy in terms of intubation success. What this study adds on this topic? • There is a very limited number of studies in the literature among pediatricians, especially in pediatricians who have never used a video laryngoscope and have limited endotracheal intubation experience. • Residents in pediatrics with limited experience in endotracheal intubation use the videolaryngoscope more effectively than the standard direct laryngoscope after appropriate training.
Pulmonary venous stenosis (PVS) is a rare and progressive foetal disease (1). It is categorised i... more Pulmonary venous stenosis (PVS) is a rare and progressive foetal disease (1). It is categorised into congenital and acquired forms. Acquired PVS occurring due to atrial fibrillation (AF) ablation and after surgical correction of pulmonary venous return anomalies has been frequently described, but limited information is available regarding congenital PVS (2). The incidence of the disease is 0.4% in patients with congenital heart disease, whereas that of acquired PVS is 10%-15% after TAPVD correction and as high as 30%-40% after AF ablation (1,2) .
Turkish Journal of Pediatric Emergency and Intensive Care Medicine, 2018
6 months of follow-up. Decompressive craniectomy should be considered without delay in children w... more 6 months of follow-up. Decompressive craniectomy should be considered without delay in children with severe head trauma with neurological deterioration or intracranial pressure elevation refractory to medical treatment and in those with herniation.
IntroductionThere have been some significant changes regarding healthcare utilization during the ... more IntroductionThere have been some significant changes regarding healthcare utilization during the COVID-19 pandemic. Majority of the reports about the impact of the COVID-19 pandemic on diabetes care are from the first wave of the pandemic. We aim to evaluate the potential effects of the COVID-19 pandemic on the severity of diabetic ketoacidosis (DKA) and new onset Type 1 diabetes presenting with DKA, and also evaluate children with DKA and acute COVID-19 infection.MethodsThis is a retrospective multi-center study among 997 children and adolescents with type 1 diabetes who were admitted with DKA to 27 pediatric intensive care units in Turkey between the first year of pandemic and pre-pandemic year.ResultsThe percentage of children with new-onset Type 1 diabetes presenting with DKA was higher during the COVID-19 pandemic (p < 0.0001). The incidence of severe DKA was also higher during the COVID-19 pandemic (p < 0.0001) and also higher among children with new onset Type 1 diabete...
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Papers by Gokcen Özcifci