All Questions
Tagged with matching case-control-study
24 questions
1
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1
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62
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How to compare cases and controls after adjusting for age differences?
I have a dataset in which I have different measures (a, b, c) and two independent variables: D which is an independent binary variable representing cases (1) and controls (0), and age is another ...
- 11
0
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0
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49
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When to use paired samples tests? Specific case in clinical research
I am working on the analysis of an observational clinical study. It is basically a control/intervention study, where the intervention group received a novel protocol. In order to assess its ...
- 303
0
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0
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47
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Can propensity score matching be used in nested case-control study?
I'm poor with epidemiological methodology and I'm working on a study that look at the effects of a binary exposure on three time-to-event outcomes in a large cohort (general population). As the ...
- 1
2
votes
1
answer
32
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Use of simple statistics for matched study designs
This might be a silly question, but I have always found this confusing. In a case-control study one selects participants to the study based on having or not having the outcome, in addition to some set ...
- 445
2
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2
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184
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Retrospective cohort study with case:control matching 1:5. Is clogit really appropriate?
I study school grades in children with brain tumors (=cases), using databases.
Every case in the database has five healthy controls, matched on sex, birth year and residency. The hypothesis is that ...
- 21
1
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0
answers
17
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Members in treatment group serve as controls for other treatment members to eliminate unmeasured confounders in pre/post observational study?
Consider a typical observational healthcare study where pre/post health outcomes among patients receiving a treatment or care program are compared to a counterfactual control group who didn't receive ...
- 6,286
0
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0
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158
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test for difference between matched pairs in 1:1 matched study
Background: I have a retrospective study (registry) that contains data on people with kidney transplant. Among these patients, we have a very small number of people with a specific genetic disease (n=...
- 173
2
votes
1
answer
370
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Propensity score matching in a case-control study: can the number of matches per patient be correlated with a matching variable?
Say I am trying to investigate the association between antidepressants and achieving recovery in a depression programme. I have an observational cohort of depressed patients enrolled in the programme ...
- 235
3
votes
1
answer
56
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Limits to how many control and treatment subjects may be paired in propensity score matching?
I'm working on a difference-in-differences project where we're matching up to 5 control subjects to each treatment subject using a combination of techniques to estimate treatment effects (ATT): exact, ...
- 6,286
2
votes
1
answer
153
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Balance diagnostics: Why not measure post-matching balance **within** matched treatment-control pairs?
I understand there are a number of techniques for evaluating post-matching balance at the covariate level: standardized mean difference (SMD), variance ratios, and empirical CDF statistics.
Are there ...
- 6,286
6
votes
1
answer
148
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Extreme differences between control group and affected group
I am reviewing an article and cannot be overly specific but it involves one group of people with a medical condition and another group without it; the dependent variables are various mental health ...
- 128k
1
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0
answers
207
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Interaction with a matching variable (time) in conditional logistic regression
Short version: I want to look at the interaction between an explanatory variable and a matching variable in my conditional logistic regression. Is that possible?
I'm doing a case-control study on risk ...
- 111
3
votes
1
answer
2k
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Matching when there are missing data
In a treatment effects framework, I have a control and treatment group with some covariates on which to match (I'm using nearest-neighbor method).
The control group has a no missing data, but some ...
- 31
1
vote
0
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20
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The appropriate match ratio between case and controls: the obsession with 1:5 [duplicate]
My intention with this question is to collect relevant references or literature for a recurrent methodological approach commonly applied in health research.
The main question is: what is the ...
- 259
1
vote
0
answers
88
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Variable ratio matching
I am working on a simulated study where I have variable number of control matches for my treatment subjects. I am new to this type of analysis. I realize after matching I can utilize logistic ...
- 11
1
vote
1
answer
6k
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3:1 matching with MatchIt in R. The number of matched control is not equal to 3 times the number of cases
Hello I'm using the MatchIt package in R
I have a total of unmatched 116 treated cases and 462 unmatcehd non-treated case
with the command
...
- 593
1
vote
1
answer
1k
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Interacting treatment variables with independent variables in matched samples
Can we interact the treatment variables with independent control variables that have been used for matching?
I have a binary treatment variable called 'medicine'. It indicates whether a person ...
- 127
1
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0
answers
24
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Matching inflation
I have data on a few millions of patients, about 1000 of them are cases, that is, they were diagnosed having a certain disease at some timepoint in their life.
I think I basically have two options:
1)...
- 89
1
vote
0
answers
670
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matched cohort with 1:n pairs - correct stratified logistic model
In this hypothetical example we have access to a database. In it cases are people with children and controls are those without kids. We want to measure the association between having children and Lung ...
- 431
0
votes
1
answer
625
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Should cohort studies in diagnosis research be age-matched?
It is clear that cohort studies in epidemiology should be matched for such variables as age, gender, etc.
However, cross-sectional cohort studies may also be used to assess the accuracy of a new ...
- 1
1
vote
1
answer
114
views
Is a comparison of patients between 2 clinics using propensity score matching a matched case control study?
I'm helping my boss design a study that will look at the effects of a clinic level intervention on a patient level outcome.
I would like to look at the effect of our intervention on one clinic (...
- 11
0
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0
answers
55
views
Matching and study design
I am currently designing a retrospective case-control study and am having some difficulty coming up with an adequate matching solution. The study assesses a specific surgical procedure and the only ...
2
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0
answers
211
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Optimal way to match cases and controls w/ multiple per strata [closed]
I need to do a matched analysis. However, I cannot find good reference for the best way of matching when each stratum may contain multiple cases and controls. As an extreme example, say we want to ...
- 765
6
votes
2
answers
751
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Review of case control matching algorithms?
Can you suggest a good review of case control matching algorithms? Algorithms that can be used to set up the matched pairs of one case and one control, or matched blocks of a case and multiple ...
- 3,363