Dihidrolipoil dehidrogenaza
| Dihidrolipoil dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.8.1.4 | ||||||||
| CAS broj | 9001-18-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dihidrolipoil dehidrogenaza (EC 1.8.1.4, LDP-Glc, LDP-Val, dehidrolipoatna dehidrogenaza, dijaforaza, dihidrolipoamidna dehidrogenaza, dihidrolipoamid:NAD+ oksidoreduktaza, dihidrolipoinska dehidrogenaza, dihidrotioktinska dehidrogenaza, lipoamidna dehidrogenaza (NADH), lipoamidna oksidoreduktaza (NADH), lipoamidna reduktaza, lipoamidna reduktaza (NADH), lipoatna dehidrogenaza, lipoinsko kiselinska dehidrogenaza, lipoilna dehidrogenaza, protein-6-N-(dihidrolipoil)lizin:NAD+ oksidoreduktaza) je enzim sa sistematskim imenom protein-N6-(dihidrolipoil)lizin:NAD+ oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- protein N6-(dihidrolipoil)lizin + NAD+ protein N6-(lipoil)lizin + NADH + H+
Ovaj enzim je flavoprotein (FAD). On je komponenta multienzimskog kompleksa 2-okso-kiselinske dehidrogenaze.
Reference
[уреди | уреди извор]- ^ Massey, V. (1963). „Lipoyl dehydrogenase”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 7 (2nd изд.). New York: Academic Press. стр. 275—306.
- ^ Massey, V., Gibson, Q.H. and Veeger, C. (1960). „Intermediates in the catalytic action of lipoyl dehydrogenase (diaphorase)”. Biochem. J. 77: 341—351. PMID 13767908.
- ^ Savage, N. (1957). „Preparation and properties of highly purified diaphorase”. Biochem. J. 67: 146—155. PMID 13471525.
- ^ Straub, F.B. (1939). „Isolation and properties of a flavoprotein from heart muscle tissue”. Biochem. J. 33: 787—792. PMID 16746974.
- ^ Perham, R.N. (2000). „Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions”. Annu. Rev. Biochem. 69: 961—1004. PMID 10966480.
- ^ Nesbitt, N.M., Baleanu-Gogonea, C., Cicchillo, R.M., Goodson, K., Iwig, D.F., Broadwater, J.A., Haas, J.A., Fox, B.G. and Booker, S.J. (2005). „Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase”. Protein Expr. Purif. 39: 269—282. PMID 15642479.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Dihydrolipoyl+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
