4-Hidroksifenilacetaldehid oksim monooksigenaza
(преусмерено са 4-hidroksifenilacetaldehid oksim monooksigenaza)
| 4-Hidroksifenilacetaldehid oksim monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.68 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-Hidroksifenilacetaldehid oksim monooksigenaza (EC 1.14.13.68, 4-hidroksibenzenacetaldehid oksimska monooksigenaza, citohrom P450II-zavisna monooksigenaza, NADPH-citohrom P450 reduktaza (CYP71E1), CYP71E1, 4-hidroksifenilacetaldehid oksim,NADPH:kiseonik oksidoreduktaza) je enzim sa sistematskim imenom (Z)-4-hidroksifenilacetaldehid oksim,NADPH:kiseonik oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (Z)-4-hidroksifenilacetaldehid oksim + NADPH + H+ + O2 (S)-4-hidroksimandelonitril + NADP+ + 2H2O
Ovaj enzim učestvuju u biosintezi cijanogenig glukozida dhurina.
Reference
[уреди | уреди извор]- ^ MacFarlane, I.J., Lees, E.M. and Conn, E.E. (1975). „The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor”. J. Biol. Chem. 250: 4708—4713. PMID 237909.
- ^ Shimada, M. & Conn, E.E. (1977). „The enzymatic conversion of p-hydroxyphenylacetaldoxime to p-hydroxymandelonitrile”. Arch. Biochem. Biophys. 180: 199—207. PMID 193443.
- ^ Busk, P.K. and Møller, B.L. (2002). „Dhurrin synthesis in sorghum is regulated at the transcriptional level and induced by nitrogen fertilization in older plants”. Plant Physiol. 129: 1222—1231. PMID 12114576.
- ^ Kristensen, C., Morant, M., Olsen, C.E., Ekstrøm, C.T., Galbraith, D.W., Møller, B.L. and Bak, S. (2005). „Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome”. Proc. Natl. Acad. Sci. USA. 102: 1779—1784. PMID 15665094.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 4-hydroxyphenylacetaldehyde+oxime+monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
