Papers by Dr. Anil Chandra Anand
Medical journal, Armed Forces India, Apr 1, 2001
2 cases of portal, splenic and superior mesenteric vein thromboses related to prolonged stay at h... more 2 cases of portal, splenic and superior mesenteric vein thromboses related to prolonged stay at high altitude are presented. Both presented initiaUy with innocuous appearing vague pain in abdomen with no physical signs. Later hepatosplenomegaly, and pleural effusion (left) was also detected. Diagnosis was based on CT scan and colour Doppler study showing thrombosed veins and porto-systemic coUateral. 1 patient developed a large splenic haernatoma requiring splenectomy. Both were managed with early anticoagulation and have done well in the short follow up.
The National Medical Journal of India, 2019
Three friends, an Indian, a Britisher and a Saudi Arabian were having dinner. The Britisher was c... more Three friends, an Indian, a Britisher and a Saudi Arabian were having dinner. The Britisher was curious, ‘Why do Indians use this tagline—‘Incredible India’? The Indian said, ‘Let me explain. Tell me what would you do in your country if a newly constructed overbridge collapses, crushing 20 people under it?’ The Britisher was amused, ‘Well, the engineer and other officials responsible for the mishap would be jailed for the rest of their lives, for sure.’ The Saudi Arabian also chipped in, ‘The irresponsible officials would be shot three times in the head and hanged in public if I had my way.’ The Indian smiled and said, ‘We have a very different approach; we will take the injured people to the hospital and beat up the doctor if anyone dies!’ The Britisher and Saudi said in a chorus, ‘Oh, incredible!’ Jokes such as this are commonly told among doctors and reflect how the medical profession feels today.
PubMed, 1993
Hemolytic uremic syndrome (HUS) is defined as microangiopathic hemolytic anemia, thrombocytopenia... more Hemolytic uremic syndrome (HUS) is defined as microangiopathic hemolytic anemia, thrombocytopenia and uremia. It is an important cause of acute renal failure (ARF) in children all over the world. The present study was carried out to assess the incidence, clinical presentation, hematological and biochemical profile of children presenting with HUS from 1987 to 1990. Out of the 100 cases who presented with ARF 22 had HUS. A majority of these children were males below 1 year of age, and had a prodromal phase of mainly gastrointestinal manifestations lasting for about a week. Anemia was a constant feature followed by bleeding diathesis, mainly melena and purpura. Neurological manifestations included altered sensorium, irritability, coma, hypertensive encephalopathy and convulsions. Renal problems mainly included oliguria, hypertension, hematuria and edema. Investigations revealed thrombocytopenia and microangiopathic hemolytic anemia in all cases. Evidence of disseminated intravascular coagulation (DIC) was observed in 3 cases as decreased fibrinogen levels, increased fibrinogen degradation products and deranged clotting studies. Blood biochemistry revealed azotemia in all cases, hyponatremia in 5 cases, hypernatremia in 3 cases and hyperkalemia in 12 cases. Stool culture showed the presence of Shigella in 8, E. coli in 6 and Klebsiella in 4 cases. Out of 22 cases of HUS, 15 were treated conservatively; of these 2 died. Both of these deaths were due to DIC 7 children were put on peritoneal dialysis; only 1 child died in this group. Factors affecting the outcome were duration of oliguria, levels of blood urea and presence of encephalopathy.(ABSTRACT TRUNCATED AT 250 WORDS)
Indian Journal of Gastroenterology, Sep 1, 2015
Purpose of review Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE... more Purpose of review Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are two types of upper gastrointestinal bleeding that may present similarly, but are managed very differently. This article reviews the pathogenesis and guidelines in management of both of these conditions with emphasis on recent advances in the field. Recent findings Off-label use of Hemospray has been shown in several case series to be useful in managing acute bleeding from PHG. Balloon-occluded retrograde transvenous obliteration presents an alternative approach for this condition. Radiofrequency ablation may be an alternative therapy to argon plasma coagulation in the endoscopic treatment of GAVE, as it consists of fewer sessions and has been shown to decrease gastrointestinal blood loss. Summary The treatment options for PHG and GAVE are constantly evolving and expanding. In this review, we present the latest approaches in the gastroenterologist's arsenal to deal with these conditions.
Journal of clinical and experimental hepatology, Mar 1, 2017
Journal of clinical and experimental hepatology, 2023
Indian Journal of Critical Care Medicine, Jun 20, 2022
Digestive Diseases and Sciences, 2010
Background/Aims Non-cirrhotic intrahepatic portal hypertension (NCIPH) is generally regarded to h... more Background/Aims Non-cirrhotic intrahepatic portal hypertension (NCIPH) is generally regarded to have a benign prognosis. We have studied a cohort followed-up at a tertiary referral center and postulate that gut-derived prothrombotic factors may contribute to the pathogenesis and prognosis of NCIPH. Methods We retrospectively analyzed prognostic indicators in 34 NCIPH patients. We also searched for associated gut diseases. Results Transplant-free survival in NCIPH patients from first presentation with NCIPH at 1, 5, and 10 years was 94% (SE: 4.2%), 84% (6.6%), and 69% (9.8%), respectively. Decompensated liver disease occurred in 53% of patients. Three (9%) patients had ulcerative colitis while five of 31 (16%) tested had celiac disease and on Kaplan-Meier analysis, celiac disease predicted reduced transplantfree survival (p = 0.018). On multivariable Cox regression analysis, independent predictors of reduced transplant-free survival were older age at first presentation with NCIPH, hepatic encephalopathy, and portal vein thrombosis. Prevalence of elevated initial serum IgA anticardiolipin antibody (CLPA) was significantly higher in NCIPH (36% of patients tested), compared to Budd-Chiari syndrome (6%) (p = 0.032, Fisher's exact test) and celiac disease without concomitant liver disease (0%) (p = 0.007). Conclusions We have identified prognostic factors and report progression to liver failure in 53% of NCIPH
Journal of Marine Medical Society, 2012
Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 2009
India has 262 medical colleges, producing over 29,000 doctors a year. Nearly half of these medica... more India has 262 medical colleges, producing over 29,000 doctors a year. Nearly half of these medical colleges have recently risen in the private sector. As a result, there is an acute shortage of medical teachers. Teaching in medical colleges was once considered immensely important. It is, however, no longer an attractive career option for a young doctor now. With private practice permitted in most colleges, teaching remains low on the priority scale for most doctors. There is quite naturally a visible effect on the quality of doctors being produced if you may, and on the young doctor's approach to this profession. It is perhaps time for us to decide then if we are indeed moving towards the light.
The National Medical Journal of India, 2019
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Papers by Dr. Anil Chandra Anand