Origem: Wikipédia, a enciclopédia livre.
PGR Estruturas disponíveis PDB Pesquisa Human UniProt: PDBe RCSB Lista de códigos id do PDB 4OAR , 1A28 , 1E3K , 1SQN , 1SR7 , 1ZUC , 2C7A , 2OVH , 2OVM , 2W8Y , 3D90 , 3G8O , 3HQ5 , 3KBA , 3ZR7 , 3ZRA , 3ZRB , 4A2J , 4APU , 5CC0
Identificadores Nomes alternativos PGR , recetores de progesterona, PR, NR3C3IDs externos OMIM: 607311 HomoloGene: 713 GeneCards: PGR Targeted by Drug dydrogesterone , Levonorgestrel , Medroxiprogesterona , noretindrona , progesterona , promegestone , tanaproget , mifepristona , acetato de ulipristal , asoprisnil , norelgestromin , nomegestrol , segesterone acetate , progesterona , onapristone [ 1] Ontologia genética Função molecular • DNA binding • sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • ATPase binding • zinc ion binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • metal ion binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • steroid hormone receptor activity • steroid binding • GO:0001948, GO:0016582 ligação a proteínas plasmáticas • enzyme binding • signaling receptor binding • lipid binding • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Componente celular • citoplasma • membrane • cariolinfa • mitochondrial outer membrane • mitocôndria • núcleo celular • citosol Processo biológico • GO:0009373 regulation of transcription, DNA-templated • cell-cell signaling • negative regulation of gene expression • transcription, DNA-templated • transcription initiation from RNA polymerase II promoter • GO:0072468 transdução de sinal • steroid hormone mediated signaling pathway • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • ovulation from ovarian follicle • epithelial cell maturation • Mamogênese • Parácrino • lung alveolus development • regulation of epithelial cell proliferation • progesterone receptor signaling pathway • tertiary branching involved in mammary gland duct morphogenesis Sources:Amigo / QuickGO
Wikidata
Os recetores de progesterona , também denominados NR3C3 (recetor nuclear subfamília 3, grupo C, membro 3) são proteínas presentes no interior das células do tecido reprodutivo feminino e ativada pela hormona progesterona .[ 3]
Referências