Name	Known for
Iain Armitage Sheldon Cooper Sheldon Cooper See fewer	Young Sheldon (2017)
Zoe Perry Mary Cooper Mary Cooper See fewer	Young Sheldon (2017)
Lance Barber George Cooper Sr. George Cooper Sr. See fewer	Gangster Squad (2013)
Montana Jordan Georgie Cooper Georgie Cooper See fewer	Young Sheldon (2017)
Raegan Revord Missy Cooper Missy Cooper See fewer	Young Sheldon (2017)
Emily Osment Mandy McAllister Mandy McAllister See fewer	Hannah Montana: The Movie (2009)
Wyatt McClure Billy Sparks Billy Sparks See fewer	I See You (II) (2019)
Annie Potts Connie 'Meemaw' Tucker Connie 'Meemaw' Tucker See fewer	Ghostbusters (1984)
Jim Parsons Sheldon Cooper (voice) Sheldon Cooper (voice) See fewer	The Big Bang Theory (2007)
Ed Begley Jr. Dr. Linkletter Dr. Linkletter See fewer	A Mighty Wind (2003)
Wendie Malick President Hagemeyer President Hagemeyer See fewer	The American President (1995)
Melissa Peterman Brenda Sparks Brenda Sparks See fewer	Fargo (1996)
Dhruv Uday Singh Dr. Prakash Dr. Prakash See fewer	Good Trouble (2019)
Brandee Steger Dr. Bell Dr. Bell See fewer	The Baby-Sitters Club (2020)
Wallace Shawn Dr. John Sturgis Dr. John Sturgis See fewer	My Dinner with Andre (1981)
Stewart Skelton Dr. Adams Dr. Adams See fewer	For All Mankind (2019)
Janet Song Dr. Cheng Dr. Cheng See fewer	Kings (2017)
Jim Hanna Dr. Hayes Dr. Hayes See fewer	The Dropout (2022)
Wil Bowers Dr. Thompson Dr. Thompson See fewer	I Think You Should Leave with Tim Robinson (2019)
Penny L. Moore Dr. Evans Dr. Evans See fewer	Frost/Nixon (2008)