Papers by Chang-Kai Chen 陳昶愷
PeerJ, 2017
Background The cause−effect relation between periodontal inflammatory disease (PID) and Parkinson... more Background The cause−effect relation between periodontal inflammatory disease (PID) and Parkinson’s disease (PD) remains uncertain. The purpose of our study was to investigate the association between PID and PD. Methods We conducted a retrospective matched-cohort study by using Taiwan’s National Health Insurance Research Database. We identified 5,396 patients with newly diagnosed PID during 1997–2004 and 10,792 cases without PID by matching sex, age, index of year (occurrence of PID), and comorbidity. Cox proportional hazard regression was used to evaluate the risk of subsequent PD. Results At the final follow-up, a total of 176 (3.26%) and 275 (2.55%) individuals developed PD in the case and control groups, respectively. Patients with PID have a higher risk of developing PD (adjusted hazard ratio = 1.431, 95% CI [1.141–1.794], p = 0.002). Discussion Our results show that PID is associated with an increased risk of developing PD. Whilst these findings suggest that reducing PID may m...
Journal of Medical Sciences, 2017
Background: The evaluation of periapical radiographic evidence of these foramina might be helpful... more Background: The evaluation of periapical radiographic evidence of these foramina might be helpful to avoid hemorrhaging of the highly vascularized regions of the floor of the mouth. Accuracy and reliability of the dental radiography in depicting the interalveolar medial foramina on 28 dry mandibles was tested in this study. Materials and Methods: The 28 mandibles were radiographically examined for the presence of median and lateral foramina that were interalveolar. The foramina diameters and the distance of the foramen to the cementoenamel junction, and to the alveolar bone crest, were measured. Two radiographic images of the symphysis areas were obtained, with and without the insertion of metal wires into the foramina. On the radiographic films, the presence of the foramina was identified and marked by two periodontists. The accuracy, sensitivity, specificity, interobserver reliability and the agreement of the readings between the diagnostic films and the films with wire insertions were analyzed. Results: Two to four foramina were observed on the lingual surfaces in the symphysis areas in 27 dry skulls. Among the 52 median foramina, 22 and 21 foramina were identified by observers 1 and 2, respectively. The accuracy, sensitivity, and specificity for the identification of the foramina were 41.1%, 42.3%, and 25.0%, respectively, for observer 1, and 37.5%, 40.4%, and 0.0%, respectively, for observer 2. The interobserver reliability was 0.57 (Kappa value). The readings for the diagnostic films and those for the films with wire insertions showed no agreement, regardless of the observer. Conclusions: Dental radiography revealed the presence of interalveolar foramina in 28 skulls; nonetheless, this result should be interpreted cautiously, as the accuracy was <50%.
The International Journal of Oral & Maxillofacial Implants
Computer-aided surgery under navigation system guidance is widely applied in dental implant proce... more Computer-aided surgery under navigation system guidance is widely applied in dental implant procedures. However, the accuracy of drilling with such navigation systems has not been comparatively evaluated alongside those of laboratory guide-based and freehand drilling. Therefore, this study aimed to compare the accuracies of these three drilling systems. Materials and Methods: A navigation system, a laboratory guide, and freehand drilling were used to drill 150 holes on 30 cast models. Two master modelsone each for the maxilla and mandible-were prepared with the idea of placing five implants per cast. After drilling five holes on each cast, postoperative cone beam computed tomography images were acquired to measure the magnitude of errors. Results: The navigation system and laboratory guide were more accurate than freehand placement with respect to total errors at the entry and apex, lateral error at the apex, and angular error. The navigation system was more accurate than the laboratory guide with respect to angular error. Laboratory guide-based drilling was more accurate than freehand drilling in terms of lateral error at entry. Conclusion: In comparison with the laboratory guide and freehand placement, the navigation system exhibited lower angular and axial errors. Despite its higher accuracy, the navigation system requires the operator to pay greater attention.
Erbium:YAG laser melanin pigmentation gingivectomy gingivectomy with free gingival autografting a... more Erbium:YAG laser melanin pigmentation gingivectomy gingivectomy with free gingival autografting acellular dermal martrix allografts electrosurgery cryosurgery abrasion with diamond bur
TENCON 2007 - 2007 IEEE Region 10 Conference, 2007
Page 1. The Design and Implementation of IPSec Conflict Avoiding and Recovering System Hung-Min S... more Page 1. The Design and Implementation of IPSec Conflict Avoiding and Recovering System Hung-Min Sun1, Shih-Ying Chang1, Yao-Hsin Chen1, Bing-Zhe He1, Cheng-Kai Chen2 1Dept. ... 134141, 2006. [4]. E. Al-Shaer, H. Hamed, R. Boutaba, M. Hasan, Conflict ...
Journal of Dental Sciences, 2013
Fear of needle injection is one of the most common problems to affect dental procedures. The pati... more Fear of needle injection is one of the most common problems to affect dental procedures. The patient in this study was a 59-year-old man with contributory medical problems and smoking habits. An Er:YAG laser was used for biopsy of the right buccal tissue and tongue under topical anesthesia (Benzocaine 20%) for 1 minute without needle injection. During laser treatment, only slight bleeding occurred, eliminating the need for suturing. Histopathological examination revealed squamous cell hyperplasia without dysplasia and chronic inflammatory cell infiltration, and shrinkage and crush cells in the cutting margin. Postoperative advantages included lack of swelling, bleeding, and pain, and good wound healing.
Inorganic Chemistry, 2011
A series of Re(I) complexes, [Re(CO)(3)Cl(HPB)] (1), [Re(CO)(3)(PB)H(2)O] (2), [Re(CO)(3)(NO(3))(... more A series of Re(I) complexes, [Re(CO)(3)Cl(HPB)] (1), [Re(CO)(3)(PB)H(2)O] (2), [Re(CO)(3)(NO(3))(PB-AuPPh(3))] (3), and [Re(CO)(3)(NO(3))(PB)Au(dppm-H)Au](2) (4) [HPB = 2-(2&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;-pyridyl)benzimidazole; dppm = 2,2&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;-bis(diphenylphosphinomethane)], have been synthesized and characterized by X-ray diffraction. Complex 1, which exhibits interesting pH-dependent spectroscopic and luminescent properties, was prepared by reacting Re(CO)(5)Cl with an equimolar amount of 2-(2&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;-pyridyl)benzimidazole. The imidazole unit in complex 1 can be deprotonated to form the imidazolate unit to give complex 2. Addition of 1 equiv of AuPPh(3)(NO(3)) to complex 2 led to the formation of a heteronuclear complex 3. Addition of a half an equivalent of dppm(Au(NO(3)))(2) to complex 2 yielded 4. In both 3 and 4, the imidazolate unit acts as a multinuclear bridging ligand. Complex 4 is a rare and remarkable example of a Re(2)Au(4) aggregate in combination with μ(3)-bridging 2-(2&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;-pyridyl)benzimidazolate. Finally, complex 2 has been used to examine the Hg(2+)-recognition event among group 12 metal ions. Its reversibility and selectivity toward Hg(2+) are also examined.
Purpose: Computer-aided surgery under navigation system guidance is widely applied in dental impl... more Purpose: Computer-aided surgery under navigation system guidance is widely applied in dental implant procedures. However, the accuracy of drilling with such navigation systems has not been comparatively evaluated alongside those of laboratory guide-based and freehand drilling. Therefore, this study aimed to compare the accuracies of these three drilling systems. Materials and Methods: A navigation system, a laboratory guide, and freehand drilling were used to drill 150 holes on 30 cast models. Two master models-one each for the maxilla and mandible-were prepared with the idea of placing five implants per cast. After drilling five holes on each cast, postoperative cone beam computed tomography images were acquired to measure the magnitude of errors. Results: The navigation system and laboratory guide were more accurate than freehand placement with respect to total errors at the entry and apex, lateral error at the apex, and angular error. The navigation system was more accurate than the laboratory guide with respect to angular error. Laboratory guide-based drilling was more accurate than freehand drilling in terms of lateral error at entry. Conclusion: In comparison with the laboratory guide and freehand placement, the navigation system exhibited lower angular and axial errors. Despite its higher accuracy, the navigation system requires the operator to pay greater attention.
the international journal of periodontics and restorative dentistry, 2017
This study evaluated use of a solid-state laser to avoid the flap technique and suturing. An Er:Y... more This study evaluated use of a solid-state laser to avoid the flap technique and suturing. An Er:YAG laser was used in 26 consecutive patients referred for osseous crown lengthening in 32 posterior teeth. The distance from the planned restoration margin to the alveolar crest (B) satisfied a 3-mm dentogingival complex. No tissue necrosis and no significant change in the distance from the gingival margin to B or probing depth were detected at 3 and 6 months. Minimally invasive Er:YAG laser surgery decreases the time needed to establish the gingival margin necessary for definitive restoration.
This study evaluated use of a solid-state laser to avoid the ap technique
and suturing. An Er:YA... more This study evaluated use of a solid-state laser to avoid the ap technique
and suturing. An Er:YAG laser was used in 26 consecutive patients referred
for osseous crown lengthening in 32 posterior teeth. The distance from
the planned restoration margin to the alveolar crest (B) satis ed a 3-mm dentogingival complex. No tissue necrosis and no signi cant change in the distance from the gingival margin to B or probing depth were detected at
3 and 6 months. Minimally invasive Er:YAG laser surgery decreases the time needed to establish the gingival margin necessary for de nitive restoration.
對於軟硬組織，要調好適當的能量與波長，雷射在牙醫植體學的應用是大有可為的。無疑的，關於雷射之物理學、雷射與組織間交互作用之廣泛知識的了解，適當的訓練都是雷射應用在日常治療必要的條件，更要注意安全... more 對於軟硬組織，要調好適當的能量與波長，雷射在牙醫植體學的應用是大有可為的。無疑的，關於雷射之物理學、雷射與組織間交互作用之廣泛知識的了解，適當的訓練都是雷射應用在日常治療必要的條件，更要注意安全措施，避免雷射傷害，以及不必要的醫療糾紛。有了這些雷射的知識，雷射便可以用來治療植體周圍炎，處理好導致植體失敗的植體周圍發炎反應，甚至能夠增進骨整合。
二極體雷射又稱作軟組織雷射，因其擁有牙齦手術切割的能力，裝置尺寸小且費用相對較低，在部分臨床牙醫師之間已漸漸風行。軟組織雷射的防潮控制(moisture control)與止血(hemostas... more 二極體雷射又稱作軟組織雷射，因其擁有牙齦手術切割的能力，裝置尺寸小且費用相對較低，在部分臨床牙醫師之間已漸漸風行。軟組織雷射的防潮控制(moisture control)與止血(hemostasis)的能力，使臨床牙醫師切割牙齦組織、施行美觀性牙冠增長術(esthetic crown lengthening)、與降低牙齦溝(gingival troughing)等術式容易上手，讓臨床牙醫師們對於雷射手術技術的操作更容易熟悉。軟組織雷射在牙科領域中也漸漸被接受，他們有潛力在降低生物性副作用的情況下，完成贗復前牙齦處理。這篇文章強調了二極體雷射於上顎前牙的牙周-贗復技術中的使用。針對他們臨床優點的評估，討論其使用在美容牙科治療的好處。
鼎友
相較於用傳統的手術刀做軟組織的修整,雷射能提供更多的優點。例如:促進傷口凝血、密封淋巴組織、在組織剝落時同時對傷口消毒及維持手術區的清潔。雷射手術大多只需要表面塗佈麻醉藥,適用於齒顎矯正診所。手... more 相較於用傳統的手術刀做軟組織的修整,雷射能提供更多的優點。例如:促進傷口凝血、密封淋巴組織、在組織剝落時同時對傷口消毒及維持手術區的清潔。雷射手術大多只需要表面塗佈麻醉藥,適用於齒顎矯正診所。手術期間有效減少出血量、腫脹程度,並且不需要縫合以及牙周敷料。某些研究文獻報告指出雷射手術造成的疤痕組織較傳統手術刀來得少,當然,也有持反面意見的研究文獻。但大多數患者表示相較於傳統手術,雷射在術後較無不適感,說話及進食狀況亦無明顯影響,術後疼痛所需的止痛藥也較少。
laser dentistry
在1987年，Mombelli等學者定義「植體周圍炎」為在骨整合之植體周圍的軟、硬組織之破壞發炎過程，而且會導致植體周圍囊袋的形成和支持骨的喪失。在軟組織方面，發炎的狀態會有探測後流血，有時甚至... more 在1987年，Mombelli等學者定義「植體周圍炎」為在骨整合之植體周圍的軟、硬組織之破壞發炎過程，而且會導致植體周圍囊袋的形成和支持骨的喪失。在軟組織方面，發炎的狀態會有探測後流血，有時甚至有紅、腫及膿的出現，而疼痛通常是不易察覺的。在硬組織方面，植體周圍炎所產生的缺損通常是在植體周圍呈現碗碟狀。由於在植體底部仍有骨整合，所以初期沒有搖動的情形，若破壞至骨整合喪失，則會有顯著搖動。而前期的「植體周圍黏膜炎」則是指植體周圍軟組織之可逆發炎情形
laser dentistry
因雷射優越的物理特性,不斷有新的雷射技術及創新的應用領域,例如電子研發、機械 加工、醫療應用、通訊設備及半導體製作等領域。而雷射也有潛在的危害包括: 高壓電 擊、電路失火,零件爆裂、有毒氣體及煙... more 因雷射優越的物理特性,不斷有新的雷射技術及創新的應用領域,例如電子研發、機械 加工、醫療應用、通訊設備及半導體製作等領域。而雷射也有潛在的危害包括: 高壓電 擊、電路失火,零件爆裂、有毒氣體及煙塵粒子都是雷射操作的危害因子。對於人體而 言,常見的危害是皮膚傷害及眼睛受損,如視網膜灼傷可能造成視力損失或失明。雷射 操作主要的重點,是防止意外之設計及管理制度的建立,藉由雷射安全級數的分類,可 以確保雷射操作人員的安全與健康。
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Papers by Chang-Kai Chen 陳昶愷
and suturing. An Er:YAG laser was used in 26 consecutive patients referred
for osseous crown lengthening in 32 posterior teeth. The distance from
the planned restoration margin to the alveolar crest (B) satis ed a 3-mm dentogingival complex. No tissue necrosis and no signi cant change in the distance from the gingival margin to B or probing depth were detected at
3 and 6 months. Minimally invasive Er:YAG laser surgery decreases the time needed to establish the gingival margin necessary for de nitive restoration.
and suturing. An Er:YAG laser was used in 26 consecutive patients referred
for osseous crown lengthening in 32 posterior teeth. The distance from
the planned restoration margin to the alveolar crest (B) satis ed a 3-mm dentogingival complex. No tissue necrosis and no signi cant change in the distance from the gingival margin to B or probing depth were detected at
3 and 6 months. Minimally invasive Er:YAG laser surgery decreases the time needed to establish the gingival margin necessary for de nitive restoration.