Cardiology

Congenital heart defects caused by problems with the placenta

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them. Previous research had suggested that some heart defects could be triggered by problems with the ...

Medical research

Gene therapy shows promise for improving placental function

A gene therapy approach to boosting the placenta is safe in monkeys, according to a new, short-term study, bringing the potential treatment closer to improving birthweights of human babies and sparing them the complications ...

Medical research

Six proteins may hold key to diagnosing early-onset preeclampsia

Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, ...

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Placenta

The placenta is an organ unique to mammals that connects the developing fetus to the uterine wall. The placenta supplies the fetus with oxygen and food, and allows fetal waste to be disposed of via the maternal kidneys. The word placenta comes from the Latin for cake, from Greek plakóenta/plakoúnta, accusative of plakóeis/plakoús - πλακόεις, πλακούς, "flat, slab-like", referring to its round, flat appearance in humans. Protherial (egg-laying) and metatherial (marsupial) mammals produce a choriovitelline placenta that, while connected to the uterine wall, provides nutrients mainly derived from the egg sac. The placenta develops from the same sperm and egg cells that form the fetus, and functions as a fetomaternal organ with two components, the fetal part (Chorion frondosum), and the maternal part (Decidua basalis).

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