(Q7914515)

Vandetanib (English)

18 November 2016

C₂₂H₂₄BrFN₄O₂

1 reference

Vandetanib (English)

18 November 2016

CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

1 reference

medical condition treated

Vandetanib (English)

18 November 2016

1 reference

14 February 2018

Tuberculosis (possibly)

1 reference

Drug Indications Extracted from FAERS

2 October 2018

6 April 2011

Food and Drug Administration

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/YO460OQ37K

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022405s010lbl.pdf

significant drug interaction

amiodarone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

toremifene

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorpromazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

anagrelide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

moxifloxacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

dronedarone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

crizotinib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

zuclopenthixol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pasireotide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ondansetron

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-hydroxyzine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-methadone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

arsenic trioxide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

disopyramide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sotalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

droperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

haloperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-citalopram

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pentamidine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

mefloquine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

domperidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fingolimod

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ivabradine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amiodarone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ivabradine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-methadone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

arsenic trioxide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

disopyramide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sotalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

droperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

haloperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fingolimod

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-citalopram

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fosphenytoin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

epidermal growth factor receptor

subject has role

enzyme inhibitor

1 reference

kinase insert domain receptor

17 August 2016

subject has role

enzyme inhibitor

1 reference

17 August 2016

1 reference

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

17 August 2016

legal status (medicine)

boxed warning

1 reference

reference URL

Australian pregnancy category D

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Vandetanib

last update

28 June 2018

subject has role

protein kinase inhibitors

1 reference

5 March 2018

Vandetanib

0 references

Identifiers

InChI

InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)

1 reference

Vandetanib (English)

18 November 2016

2 references

Vandetanib (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

443913-73-3

2 references

vandetanib (English)

18 November 2016

https://commonchemistry.cas.org/detail?cas_rn=443913-73-3

9 April 2021

1 reference

Vandetanib (English)

18 November 2016

2 references

Vandetanib (English)

18 November 2016

Reaxys registry number

9161676

1 reference

vandetanib (English)

19 October 2016

mapping relation type

2 references

VANDETANIB (English)

18 November 2016

International Chemical Identifier

InChI

InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)

1 reference

VANDETANIB (English)

18 November 2016

2 references

inferred from InChIKey

splash10-000i-0293000000-9037b32a179af5e7ba9a

1 reference

0 references

HSDB ID

8198

1 reference

Hazardous Substances Data Bank

28 October 2019

Vandetanib (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.195.611

27 December 2018

ECHA Substance Infocard ID

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine (English)

quotation

CAS no.: 443913-73-3 (English)

100.195.611

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.195.611

27 December 2018

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine (English)

quotation

CAS no.: 443913-73-3 (English)

1 reference

Vandetanib (English)

publication date

17 November 2015

1 reference

vandetanib (English)

18 November 2016

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

0 references

RxNorm ID

1098413

1 reference

vandetanib (English)

18 November 2016

1 reference

2 references

vandetanib (English)

18 November 2016

MedlinePlus drug identifier

0 references

1 reference

vandetanib (English)

18 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

vandetanib (English)

19 October 2016

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

2IVU (English)

UK Parliament thesaurus ID

19 October 2016

434250

subject named as

Vandetanib

0 references

UMLS CUI

C1628324

1 reference