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A tale of two tails: ciliary mechanotransduction in ADPKD
scientific article published on 01 June 2003
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
title
A tale of two tails: ciliary mechanotransduction in ADPKD
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
Horacio F Cantiello
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Trends in Molecular Medicine
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
234-236
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetics and pathogenesis of polycystic kidney disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-1 activates and stabilizes the polycystin-2 channel.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bending the MDCK cell primary cilium increases intracellular calcium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubule active taxanes inhibit polycystic kidney disease progression in cpk mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spectrum of mutations in the gene for autosomal recessive polycystic kidney disease (ARPKD/PKHD1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary ciliary dyskinesia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Removal of the MDCK cell primary cilium abolishes flow sensing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear and cytosolic calcium are regulated independently
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-2 is an intracellular calcium release channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microvillar ion channels: cytoskeletal modulation of ion fluxes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-2 associates with tropomyosin-1, an actin microfilament component
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycystin-2 interacts with troponin I, an angiogenesis inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of mechanotransduction in living cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900073-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1471-4914(03)00073-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
12829010
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12829010
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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