(Q73371207)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

review article

1 reference

title

Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Swapan K. Ray

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738057

31 December 2023

Edward L. Hogan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738057

31 December 2023

Naren L. Banik

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738057

31 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12738057

31 December 2023

publication date

1 May 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

3 November 2019

https://api.elsevier.com/content/article/PII:S0165017303001528?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0165-0173(03)00152-8

https://api.elsevier.com/content/article/PII:S0165017303001528?httpAccept=text/plain

31 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0165-0173(03)00152-8

Brain research. Brain research reviews

31 December 2023

published in

42

2

169–85

May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12738057

31 December 2023

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

169-185

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

Life-or-death decisions by the Bcl-2 protein family.

3 November 2019

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Death receptors: signaling and modulation

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Changes in intracellular calpastatin localization are mediated by reversible phosphorylation.

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7 January 2021

Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury.

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7 January 2021

Structure of calmodulin refined at 2.2 A resolution

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7 January 2021

Autolysis parallels activation of mu-calpain

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7 January 2021

Peptide bond specificity of calpain: proteolysis of human myelin basic protein

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7 January 2021

Proteolytic enzymes in experimental spinal cord injury

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7 January 2021

Degradation of cytoskeletal proteins in experimental spinal cord injury

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Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury

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7 January 2021

A new mechanism of methylprednisolone and other corticosteroids action demonstrated in vitro: inhibition of a proteinase (calpain) prevents myelin and cytoskeletal protein degradation

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7 January 2021

Calcium-stimulated proteolysis in myelin: evidence for a Ca2+-activated neutral proteinase associated with purified myelin of rat CNS.

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7 January 2021

The Effects of Spinal Cord Trauma on Myelin

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7 January 2021

Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical Inhibitorsa

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7 January 2021

Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration

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7 January 2021

Review of current evidence for apoptosis after spinal cord injury.

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7 January 2021

Temporal and spatial profile of caspase 8 expression and proteolysis after experimental traumatic brain injury

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7 January 2021

Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: selective localization in microglia

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7 January 2021

Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia

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7 January 2021

Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?

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7 January 2021

Effects of multi-dose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism

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7 January 2021

An electron-microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta)

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7 January 2021

Calpain: a protease in search of a function?

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7 January 2021

Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat

1 reference

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7 January 2021

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

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7 January 2021

Caspases: the executioners of apoptosis

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7 January 2021

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

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7 January 2021

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

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7 January 2021

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

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7 January 2021

Domain structure of calpain: mapping the binding site for calpastatin

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7 January 2021

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

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7 January 2021

Rat brain contains multiple mRNAs for calpastatin1

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7 January 2021

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

1 reference

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7 January 2021

Calpain expression in lymphoid cells. Increased mRNA and protein levels after cell activation

1 reference

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

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7 January 2021

Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord

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7 January 2021

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis

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7 January 2021

Caspase pathways, neuronal apoptosis, and CNS injury

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7 January 2021

Apoptosis after traumatic human spinal cord injury

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7 January 2021

Endogenous inhibitor for calcium-dependent cysteine protease contains four internal repeats that could be responsible for its multiple reactive sites

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation

1 reference

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7 January 2021

Mitochondrial participation in ischemic and traumatic neural cell death

1 reference

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7 January 2021

Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats

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7 January 2021

Interleukin-1 stimulation of astroglial proliferation after brain injury

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7 January 2021

Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS

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7 January 2021

Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation

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7 January 2021

Tissue calcium levels in CaCl2-induced myelopathy

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7 January 2021

Ca2+-accumulation in experimental spinal cord trauma

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7 January 2021

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cleavage of bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Alteration of thromboxane and prostacyclin levels in experimental spinal cord injury

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7 January 2021

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

1 reference

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7 January 2021

Limited autolysis of calcium-activated neutral protease (CANP): reduction of the Ca2+-requirement is due to the NH2-terminal processing of the large subunit

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7 January 2021

Rat calpastatin has diverged primary sequence from other mammalian calpastatins but retains functionally important sequences

1 reference

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7 January 2021

Localization of calpain immunoreactivity in senile plaques and in neurones undergoing neurofibrillary degeneration in Alzheimer's disease

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7 January 2021

Noncaspase proteases in apoptosis

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7 January 2021

Calpains (intracellular calcium-activated cysteine proteinases): structure-activity relationships and involvement in normal and abnormal cellular metabolism

1 reference

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7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

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7 January 2021

Mechanisms of calpain proteolysis following traumatic brain injury: implications for pathology and therapy: implications for pathology and therapy: a review and update

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7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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7 January 2021

Identification and characterization of inhibitory sequences in four repeating domains of the endogenous inhibitor for calcium-dependent protease.

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7 January 2021

Regulation of the calpain-calpastatin system by membranes (review).

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7 January 2021

Apoptotic and anti-apoptotic mechanisms following spinal cord injury

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7 January 2021

Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death

1 reference

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

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7 January 2021

Beneficial effect of new thiol protease inhibitors, epoxide derivatives, on dystrophic mice

1 reference

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7 January 2021

Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

1 reference

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7 January 2021

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

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7 January 2021

Free radical pathways in CNS injury

1 reference

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7 January 2021

Changes of Fas and Fas ligand immunoreactivity after compression trauma to rat spinal cord

1 reference

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7 January 2021

Role of calpain in spinal cord injury: increased mcalpain immunoreactivity in spinal cord after compression injury in the rat

1 reference

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7 January 2021

Role of calpain in spinal cord injury: increased calpain immunoreactivity in rat spinal cord after impact trauma

1 reference

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7 January 2021

Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calcium, free radicals and excitotoxins in neuronal apoptosis.

1 reference

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7 January 2021

The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Elevation of hydrogen peroxide after spinal cord injury detected by using the Fenton reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Neuronal and glial apoptosis after traumatic spinal cord injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

1 reference

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7 January 2021

Apoptosis as a mechanism of neuronal cell death following acute experimental spinal cord injury

1 reference

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7 January 2021

In Vivo Bcl-2 Oncogene Neuronal Expression in the Rat Spinal Cord

1 reference

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7 January 2021

Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Six-Hour Window of Opportunity for Calpain Inhibition in Focal Cerebral Ischemia in Rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Fas receptor and neuronal cell death after spinal cord ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

The binding of large calpastatin to biologic membranes is mediated in part by interaction of an amino terminal region with acidic phospholipids

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Proteolysis of the calcium-dependent protease inhibitor by myocardial calcium-dependent protease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

An improved purification procedure for calpastatin, the inhibitor protein specific for the intracellular calcium-dependent proteinases, calpains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Modulation of the calpain autoproteolysis by calpastatin and phospholipids

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Molecular and functional properties of a calpain activator protein specific for mu-isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Mechanism of action of a new component of the Ca(2+)-dependent proteolytic system in rat brain: the calpain activator

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Bcl-2 gene family in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpastatin immunoreactivity in the monkey and human brain of control subjects and patients with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

The Cytosol of Human Erythrocytes Contains a Highly Ca2+-Sensitive Thiol Protease (Calpain I) and Its Specific Inhibitor Protein (Calpastatin)1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain-calpastatin interactions in epidermoid carcinoma KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Fragmentation of an endogenous inhibitor upon complex formation with high- and low-Ca2+-requiring forms of calcium-activated neutral proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

The role of calcium in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calcium-activated neutral proteinases as regulators of cellular function. Implications for Alzheimer's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cytokines and metabolic dysfunction after severe head injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Therapeutic strategies targeting caspase inhibition following spinal cord injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain inhibition by peptide epoxides

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Structural and functional aspects of calcium homeostasis in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Identification of two calpastatin forms in rat skeletal muscle and their susceptibility to digestion by homologous calpains.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Alterations in immune cell phenotype and function after experimental spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Oxidative stress and Ca2+ influx upregulate calpain and induce apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

E-64-d prevents both calpain upregulation and apoptosis in the lesion and penumbra following spinal cord injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Increased calpain expression is associated with apoptosis in rat spinal cord injury: calpain inhibitor provides neuroprotection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Inhibition of calpain-mediated apoptosis by E-64 d-reduced immediate early gene (IEG) expression and reactive astrogliosis in the lesion and penumbra following spinal cord injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cell death in spinal cord injury (SCI) requires de novo protein synthesis. Calpain inhibitor E-64-d provides neuroprotection in SCI lesion and penumbra

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain activity and translational expression increased in spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Diverse stimuli induce calpain overexpression and apoptosis in C6 glioma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpeptin and methylprednisolone inhibit apoptosis in rat spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Neuroprotection by the inhibition of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Up- and down-regulation of calpain inhibitor polypeptide, calpastatin, in postischemic hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain: new perspectives in molecular diversity and physiological-pathological involvement.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Different susceptibility of red cell membrane proteins to calpain degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Modulation of calpastatin specificity in rat tissues by reversible phosphorylation and dephosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cathepsin B-mediated activation of the proinflammatory caspase-11.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Increased calpain I-mediated proteolysis, and preferential loss of dephosphorylated NF200, following traumatic spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Pretreatment with Calpain Inhibitor CEP-4143 Inhibits Calpain I Activation and Cytoskeletal Degradation, Improves Neurological Function, and Enhances Axonal Survival After Traumatic Spinal Cord Injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Serial killers: ordering caspase activation events in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Downregulation of Calpastatin in Rat Heart after Brief Ischemia and Reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Rapid Calpain I Activation and Cytoskeletal Protein Degradation Following Traumatic Spinal Cord Injury: Attenuation with Riluzole Pretreatment

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Extracellular calcium activity in the injured spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calcium-activated neutral protease and its endogenous inhibitor. Activation at the cell membrane and biological function

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

A novel aspect of calpain activation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Prolongation of life span of dystrophic hamster by cysteine proteinase inhibitor, loxistation (EST)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

The calpain cascade. Mu-calpain activates m-calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calcium-mediated cell injury and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Limited proteolysis of bovine myelin basic protein by calcium-dependent proteinase from bovine spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Low-Molecular-Weight Enzyme Inhibitors of Microbial Origin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Developing selective inhibitors of calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Production of tumor necrosis factor in spinal cord following traumatic injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Differential activation of microglia after experimental spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Calpain activation is upstream of caspases in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Leukotriene B4 release and polymorphonuclear cell infiltration in spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Caspase-dependent apoptotic pathways in CNS injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

The hydroxyl radical scavenger Nicaraven inhibits glutamate release after spinal injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cellular localization of tumor necrosis factor-alpha following acute spinal cord injury in adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Potassium and calcium changes in injured spinal cords

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Extracellular calcium ionic activity in experimental spinal cord contusion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Cytoskeletal disruption following contusion injury to the rat spinal cord.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: a casein zymography study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Involvement of cellular proteolytic machinery in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Increased interleukin-1beta converting enzyme expression and activity in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Characterization of a brain calcium-activated protease that degrades neurofilament proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2803%2900152-8

7 January 2021

Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors

19

1 reference

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Involvement of lipid peroxidation in CNS injury

31 December 2023

28

1 reference

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All four repeating domains of the endogenous inhibitor for calcium-dependent protease independently retain inhibitory activity. Expression of the cDNA fragments in Escherichia coli

31 December 2023

52

1 reference

https://api.crossref.org/works/10.1016/S0165-0173(03)00152-8

Lysosomal activity in experimental spinal cord trauma: an ultrastructural cytochemical evaluation

31 December 2023

58

1 reference

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Calcium-dependent proteases: an enzyme system active at cellular membranes?

31 December 2023

113

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Molecular mechanisms in the pathogenesis of traumatic brain injury

31 December 2023

149

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Caspase inhibition: a potential therapeutic strategy in neurological diseases

31 December 2023

159

1 reference

https://api.crossref.org/works/10.1016/S0165-0173(03)00152-8

Proteolysis of protein kinase C by calpain: effect of acidic phospholipids

31 December 2023

164

1 reference

https://api.crossref.org/works/10.1016/S0165-0173(03)00152-8

Calpain: novel family members, activation, and physiologic function

31 December 2023

188

1 reference

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31 December 2023

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12738057%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference