(Q64885759)

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Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.

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5 November 2019

Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747890%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Samuel H. Wilson

7

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5 November 2019

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Latham GJ

1

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5 November 2019

Forgacs E

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5 November 2019

Beard WA

3

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5 November 2019

Prasad R

4

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5 November 2019

Bebenek K

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5 November 2019

Kunkel TA

6

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5 November 2019

Lloyd RS

8

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5 November 2019

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1 May 2000

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

275

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5 November 2019

20

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5 November 2019

15025-15033

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5 November 2019

Sliding clamps of DNA polymerases

1 reference

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Smart machines at the DNA replication fork.

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Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit

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The accuracy of reverse transcriptase from HIV-1.

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Effect of human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein on HIV-1 reverse transcriptase activity in vitro

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The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

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21 January 2018

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

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21 January 2018

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

1 reference

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21 January 2018

Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

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21 January 2018

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

1 reference

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21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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21 January 2018

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

1 reference

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21 January 2018

A minor groove binding track in reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000279200

21 January 2018

Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000279200

21 January 2018

Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000279200

21 January 2018

Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis

1 reference

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21 January 2018

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

1 reference

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21 January 2018

Major Groove (R)-.alpha.-(N6-Adenyl)styrene Oxide Adducts in an Oligodeoxynucleotide Containing the Human n-ras Codon 61 Sequence: Conformations of the R(61,2) and R(61,3) Sequence Isomers from 1H NMR

1 reference

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21 January 2018

Major groove (S)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the S(61,2) and S(61,3) sequence isomers from 1H NMR

1 reference

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21 January 2018

Crystal Structures of Human DNA Polymerase β Complexed with Gapped and Nicked DNA: Evidence for an Induced Fit Mechanism,

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21 January 2018

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

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21 January 2018

Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

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21 January 2018

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

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21 January 2018

An expanded model of replicating human immunodeficiency virus reverse transcriptase

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21 January 2018

The Efficiency of Translesion Synthesis Past Single Styrene Oxide DNA Adducts in Vitro Is Polymerase-Specific

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Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization

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21 January 2018

Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity

1 reference

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21 January 2018

Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts

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DNA curvature controls termination of plus strand DNA synthesis at the centre of HIV-1 genome

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21 January 2018

Compression of the DNA minor groove is responsible for termination of DNA synthesis by HIV-1 reverse transcriptase

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M000279200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747890%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747890%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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