(Q61813977)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658430%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

title

Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1 (English)

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19 April 2020

0 references

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1

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Simona Federica Spampinato

19 April 2020

6

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19 April 2020

Sara Merlo

7

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19 April 2020

Giuseppe Lazzarino

9

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19 April 2020

Maria Angela Sortino

10

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19 April 2020

8

Filippo Drago

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19 April 2020

author name string

Claudia G Fresta

2

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19 April 2020

Nicolò Musso

3

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19 April 2020

Mariaconcetta Giambirtone

4

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19 April 2020

Margherita Grasso

5

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19 April 2020

Susan M Lunte

11

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19 April 2020

Filippo Caraci

12

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19 April 2020

language of work or name

English

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publication date

17 January 2019

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19 April 2020

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19 April 2020

volume

8

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19 April 2020

issue

1

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Creative Commons Attribution 4.0 International

19 April 2020

page(s)

64

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copyright license

start time

17 January 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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12 December 2020

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

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12 December 2020

MHC class II-positive microglia in human brain: association with Alzheimer lesions

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12 December 2020

Free radical scavenging activity of carnosine

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12 December 2020

Superoxide-scavenging activity of carnosine in the presence of copper and zinc ions

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12 December 2020

Non‐enzymatic glycosylation of the dipeptide l‐carnosine, a potential anti‐protein‐cross‐linking agent

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12 December 2020

Evidence that Aβ42 is the real culprit in alzheimer's disease

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12 December 2020

Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules

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12 December 2020

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

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12 December 2020

Kinetic theory of fibrillogenesis of amyloid β-protein

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12 December 2020

Evidence for a direct interaction of superoxide anion radical with carnosine

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12 December 2020

Neurofibrillary tangles and Alzheimer's disease.

1 reference

12 December 2020

Carnosine: its properties, functions and potential therapeutic applications.

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12 December 2020

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease

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12 December 2020

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

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12 December 2020

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

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12 December 2020

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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12 December 2020

Microglia: activation and their significance in the central nervous system

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12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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12 December 2020

Superoxide production and expression of nox family proteins in human atherosclerosis

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12 December 2020

Zinc suppresses IL-6 synthesis by prostaglandin F2alpha in osteoblasts: inhibition of phospholipase C and phospholipase D.

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12 December 2020

Reaction of carnosine with aged proteins: another protective process?

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12 December 2020

CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study

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12 December 2020

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

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12 December 2020

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis

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12 December 2020

Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain

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12 December 2020

iNOS-mediated nitric oxide production and its regulation

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12 December 2020

Nitric oxide pathways in Alzheimer's disease and other neurodegenerative dementias

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12 December 2020

Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration

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12 December 2020

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

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12 December 2020

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

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12 December 2020

Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease

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12 December 2020

TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts.

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12 December 2020

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

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12 December 2020

The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders.

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12 December 2020

Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders

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12 December 2020

Protective effects of L- and D-carnosine on alpha-crystallin amyloid fibril formation: implications for cataract disease.

1 reference

12 December 2020

Inhibitory effect of carnosine and N-acetyl carnosine on LPS-induced microglial oxidative stress and inflammation

1 reference

12 December 2020

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

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12 December 2020

Growth factors decrease in subjects with mild to moderate Alzheimer's disease (AD): potential correction with dehydroepiandrosterone-sulphate (DHEAS).

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12 December 2020

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

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12 December 2020

Methods and models in neurodegenerative and systemic protein aggregation diseases

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12 December 2020

Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological strategies

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12 December 2020

Mitochondrial superoxide: a key player in Alzheimer's disease

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12 December 2020

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

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12 December 2020

Decreased expression of GRAF1/OPHN-1-L in the X-linked alpha thalassemia mental retardation syndrome.

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12 December 2020

The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology

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12 December 2020

Neuroinflammatory processes in Alzheimer's disease

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12 December 2020

Transforming growth factor beta and soluble endoglin in the healthy senior and in Alzheimer's disease patients.

1 reference

12 December 2020

Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mG

1 reference

12 December 2020

Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice

1 reference

12 December 2020

Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity

1 reference

12 December 2020

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

1 reference

12 December 2020

Carnosine protects neurons against oxidative stress and modulates the time profile of MAPK cascade signaling.

1 reference

12 December 2020

Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where

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12 December 2020

Synaptotoxic amyloid-β oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease?

1 reference

12 December 2020

Protective effect of carnosine on subcortical ischemic vascular dementia in mice.

1 reference

12 December 2020

Antioxidant therapies for neurodegenerative diseases: mechanisms, current trends, and perspectives

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12 December 2020

Carnosine inhibits Aβ(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster

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12 December 2020

Fucoxanthin ameliorates inflammation and oxidative reponses in microglia

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12 December 2020

Anti-aggregating effect of the naturally occurring dipeptide carnosine on aβ1-42 fibril formation

1 reference

12 December 2020

Oxidative stress and the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

An integrated microfluidic device for monitoring changes in nitric oxide production in single T-lymphocyte (Jurkat) cells

1 reference

12 December 2020

Glia: an important target for anti-inflammatory and antidepressant activity

1 reference

12 December 2020

Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation

1 reference

12 December 2020

Microchip electrophoresis with amperometric detection method for profiling cellular nitrosative stress markers.

1 reference

12 December 2020

Carnosine attenuates early brain injury through its antioxidative and anti-apoptotic effects in a rat experimental subarachnoid hemorrhage model

1 reference

12 December 2020

Protection of TGF-β1 against neuroinflammation and neurodegeneration in Aβ1-42-induced Alzheimer's disease model rats

1 reference

12 December 2020

Reversible redox modifications in the microglial proteome challenged by beta amyloid.

1 reference

12 December 2020

Indirect detection of superoxide in RAW 264.7 macrophage cells using microchip electrophoresis coupled to laser-induced fluorescence

1 reference

12 December 2020

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.

1 reference

12 December 2020

Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease

1 reference

12 December 2020

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons

1 reference

12 December 2020

Reduction of Oxidative/Nitrosative Stress in Brain and its Involvement in the Neuroprotective Effect of n-3 PUFA in Alzheimer's Disease

1 reference

12 December 2020

The Role of Oxidative Stress in Neurodegenerative Diseases

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12 December 2020

Role of oxidative stress in Alzheimer's disease

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12 December 2020

Neuroprotective Effect of Carnosine on Primary Culture of Rat Cerebellar Cells under Oxidative Stress.

1 reference

12 December 2020

Protective effects of carnosine on dehydroascorbate-induced structural alteration and opacity of lens crystallins: important implications of carnosine pleiotropic functions to combat cataractogenesis.

1 reference

12 December 2020

The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide

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12 December 2020

Receptor-mediated toxicity of human amylin fragment aggregated by short- and long-term incubations with copper ions

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12 December 2020

Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1.

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12 December 2020

Carnosine Attenuates Brain Oxidative Stress and Apoptosis After Intracerebral Hemorrhage in Rats.

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12 December 2020

Cytokine Signatures in Mucocutaneous and Ocular Behçet's Disease

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12 December 2020

Carnosine modulates nitric oxide in stimulated murine RAW 264.7 macrophages.

1 reference

12 December 2020

Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity

1 reference

12 December 2020

Molecular imaging of neuroinflammation in Alzheimer's disease and mild cognitive impairment.

1 reference

12 December 2020

Microchip electrophoresis with laser-induced fluorescence detection for the determination of the ratio of nitric oxide to superoxide production in macrophages during inflammation.

1 reference

12 December 2020

Modulation Of Inflammation As A Way Of Delaying Alzheimer's Disease Progression: The Diet's Role

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12 December 2020

Alzheimer's disease and cytokine IL-10 gene polymorphisms: is there an association?

1 reference

12 December 2020

Microglial Activation Results in Inhibition of TGF-β-Regulated Gene Expression

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12 December 2020

Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake

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12 December 2020

Oxidative stress and the amyloid beta peptide in Alzheimer's disease

1 reference

12 December 2020

Monitoring carnosine uptake by RAW 264.7 macrophage cells using microchip electrophoresis with fluorescence detection.

1 reference

12 December 2020

Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target.

1 reference

12 December 2020

Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells.

1 reference

12 December 2020

Tetrahydroxystilbene glycoside antagonizes β-amyloid-induced inflammatory injury in microglia cells by regulating PU.1 expression.

1 reference

12 December 2020

The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death.

1 reference

12 December 2020

Protective effect of carnosine on white matter damage in corpus striatum induced by chronic cerebral hypoperfusion

1 reference

12 December 2020

Critical regulation of Th17 cell differentiation by serum amyloid-A signalling in Behcet's disease

1 reference

12 December 2020

Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells

1 reference

12 December 2020

Pivotal role of carnosine in the modulation of brain cells activity: Multimodal mechanism of action and therapeutic potential in neurodegenerative disorders

1 reference

12 December 2020

Identifiers

DOI

10.3390/CELLS8010064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658430%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658430%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

PubMed publication ID

30658430

1 reference