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The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
scientific article published in Nature
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Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
title
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
author name string
M Nikolic
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
M M Chou
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
W Lu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
B J Mayer
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
L H Tsai
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
language of work or name
English
0 references
publication date
1 September 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
published in
Nature
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
395
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
issue
6698
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
194-198
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
A brain-specific activator of cyclin-dependent kinase 5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization and developmental changes in the neuron-specific cyclin-dependent kinase 5 activator (p35nck5a) in the rat brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel disruption of cortical development in p35(-/-) mice distinct from reeler
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Dendritic Growth and Remodeling by Rho, Rac, and Cdc42
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of a New Rho Family Member in Cell Migration and Axon Guidance in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging from the Pak: the p21-activated protein kinase family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and the Actin Cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for cyclin-dependent kinases in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of p21-Activated Kinase 1 (PAK1) to Pinocytic Vesicles and Cortical Actin Structures in Stimulated Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane targeting of p21-activated kinase 1(PAK1) induces neurite outgrowth from PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific regulation of E2F family members by cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F26034
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/26034
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Dimensions Publication ID
1047528526
0 references
PubMed publication ID
9744280
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9744280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
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