(Q57372098)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

Bcl-2, via its BH4 domain, blocks apoptotic signaling mediated by mitochondrial Ras (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference

1 reference

1

1 reference

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15 December 2019

author name string

Qiang Yu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Peihong Ma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Linda Deeds

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Chang-Yan Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Douglas V Faller

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

language of work or name

English

0 references

publication date

10 December 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

15 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

volume

278

1 reference

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15 December 2019

issue

8

1 reference

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15 December 2019

page(s)

5775-5785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

15 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Insights into programmed cell death through structural biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Ras signalling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Differential regulation of discrete apoptotic pathways by Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Acylation and prenylation of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 differentially targets K-, N-, and H-Ras to mitochondria in IL-2 supplemented or deprived cells: implications in prevention of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 associates with the ras-related protein R-ras p23

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 and the Outer Mitochondrial Membrane in the Inactivation of Cytochrome c during Fas-mediated Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

BCL-2 family: regulators of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Caspase-9, Bcl-XL, and Apaf-1 Form a Ternary Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Bcl-2 phosphorylation required for anti-apoptosis function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Caspase knockouts: matters of life and death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

Stimulation of p21 ras upon T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210202200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210202200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477721%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference