(Q56262927)

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Cancer drugs to treat birth defects

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title

Cancer drugs to treat birth defects (English)

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author

Andrew Oliver Mungo Wilkie

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Andrew O M Wilkie

series ordinal

1

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language of work or name

English

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publication date

September 2007

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published in

Nature Genetics

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volume

39

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issue

9

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page(s)

1057-1059

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1057-9

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cites work

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome

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Crossref

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

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Crossref

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Strategies for silencing human disease using RNA interference

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Mechanisms underlying differential responses to FGF signaling

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis.

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reference URL

https://api.crossref.org/works/10.1038%2FNG0907-1057

retrieved

7 January 2021

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A model for the pharmacological treatment of crouzon syndrome

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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Targeting the ERK signaling pathway in cancer therapy

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7 January 2021

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Hyperactive Ras in developmental disorders and cancer

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https://api.crossref.org/works/10.1038%2FNG0907-1057

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7 January 2021

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BRAF mutation predicts sensitivity to MEK inhibition

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7 January 2021

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Identifiers

DOI

10.1038/NG0907-1057

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PubMed publication ID

17728773

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(Q56262927)

Cancer drugs to treat birth defects

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