(Q55034652)

16 June 2018

review article

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title

Diversification of haematopoietic stem cells to specific lineages. (English)

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16 June 2018

author name string

S H Orkin

series ordinal

1

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16 June 2018

publication date

1 October 2000

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16 June 2018

published in

Nature Reviews Genetics

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16 June 2018

volume

1

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16 June 2018

issue

1

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16 June 2018

page(s)

57-64

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16 June 2018

Translating stem and progenitor cell biology to the clinic: barriers and opportunities

cites work

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Development of the hematopoietic system

21 January 2018

1 reference

Mouse embryonic hematopoiesis

21 January 2018

1 reference

Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura.

21 January 2018

1 reference

The splanchnopleura/AGM region is the prime site for the generation of multipotent hemopoietic precursors, in the mouse embryo.

21 January 2018

1 reference

Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus.

21 January 2018

1 reference

Characterization of Definitive Lymphohematopoietic Stem Cells in the Day 9 Murine Yolk Sac

21 January 2018

1 reference

Murine yolk sac and bone marrow hematopoietic cells with high proliferative potential display different capacities for producing colony-forming cells ex vivo

21 January 2018

1 reference

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo

21 January 2018

1 reference

In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos

21 January 2018

1 reference

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

21 January 2018

1 reference

The genetic program of hematopoietic stem cells

21 January 2018

1 reference

Control of hematopoietic differentiation: lack of specificity in signaling by cytokine receptors

21 January 2018

1 reference

Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo.

21 January 2018

1 reference

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

21 January 2018

1 reference

GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts

21 January 2018

1 reference

The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.

21 January 2018

1 reference

Distinct C/EBP functions are required for eosinophil lineage commitment and maturation

21 January 2018

1 reference

PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors

21 January 2018

1 reference

MafB is an inducer of monocytic differentiation

21 January 2018

1 reference

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

21 January 2018

1 reference

Regulation of B lymphocyte and macrophage development by graded expression of PU.1.

21 January 2018

1 reference

Specification of Drosophila hematopoietic lineage by conserved transcription factors

21 January 2018

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Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

21 January 2018

1 reference

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

21 January 2018

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Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

21 January 2018

1 reference

Lineage commitment in lymphopoiesis

21 January 2018

1 reference

Chronic melatonin treatment and the hypothalamo-pituitary-adrenal axis in the rat: attenuation of the secretory response to stress and effects on hypothalamic neuropeptide content and release

21 January 2018

1 reference

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

21 January 2018

1 reference

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

21 January 2018

1 reference

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

21 January 2018

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Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

21 January 2018

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Spi-1/PU.1 transgenic mice develop multistep erythroleukemias

21 January 2018

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Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

21 January 2018

1 reference

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

21 January 2018

1 reference

FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

21 January 2018

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Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

21 January 2018

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Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

21 January 2018

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The Ikaros gene is required for the development of all lymphoid lineages

21 January 2018

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Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

21 January 2018

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Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

21 January 2018

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Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

21 January 2018

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Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

21 January 2018

1 reference

MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation

21 January 2018

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BSAP can repress enhancer activity by targeting PU.1 function

21 January 2018

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Activation of the beta-globin locus control region precedes commitment to the erythroid lineage

21 January 2018

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Multilineage gene expression precedes commitment in the hemopoietic system

21 January 2018

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Independent regulation of the two Pax5 alleles during B-cell development.

21 January 2018

1 reference

Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?

21 January 2018

1 reference

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

21 January 2018

1 reference

Hematopoietic potential of stem cells isolated from murine skeletal muscle

21 January 2018

1 reference

Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo

21 January 2018

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Generalized potential of adult neural stem cells

21 January 2018

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Bone marrow as a potential source of hepatic oval cells

21 January 2018

1 reference

"Vascular profiles" of regenerative and dysplastic nodules

21 January 2018

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Differentiation requires continuous regulation

21 January 2018

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Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

21 January 2018

1 reference

An early pre-liver intraembryonic source of CFU-S in the developing mouse

21 January 2018

1 reference

Dystrophin expression in the mdx mouse restored by stem cell transplantation

21 January 2018

1 reference

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo

21 January 2018

1 reference

7 January 2021

Definitive hematopoiesis is autonomously initiated by the AGM region

1 reference

7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

7 January 2021

Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter

1 reference

7 January 2021

Loops, lineage, and leukemia

1 reference

7 January 2021

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

1 reference

7 January 2021

Identifiers

DOI

10.1038/35049577

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16 June 2018

Dimensions Publication ID

1047214085

0 references

1 reference

16 June 2018