(Q53588736)

15 May 2018

title

Bace1 modulates myelination in the central and peripheral nervous system. (English)

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15 May 2018

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2

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Wendy B Macklin

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object named as

Wendy B Macklin

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15 May 2018

author name string

Xiangyou Hu

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15 May 2018

Wanxia He

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15 May 2018

Philip Wong

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15 May 2018

Bruce D Trapp

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15 May 2018

Riqiang Yan

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15 May 2018

language of work or name

English

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publication date

12 November 2006

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15 May 2018

published in

Nature Neuroscience

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15 May 2018

volume

9

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issue

12

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15 May 2018

page(s)

1520-1525

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15 May 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

cites work

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7 January 2021

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

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7 January 2021

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

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7 January 2021

Purification and cloning of amyloid precursor protein beta-secretase from human brain

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7 January 2021

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

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7 January 2021

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

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7 January 2021

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

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7 January 2021

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

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7 January 2021

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

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7 January 2021

The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate

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7 January 2021

Phosphorylation regulates intracellular trafficking of beta-secretase

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7 January 2021

Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

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7 January 2021

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

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7 January 2021

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

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7 January 2021

BACE (beta-secretase) modulates the processing of APLP2 in vivo

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7 January 2021

The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

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7 January 2021

beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

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7 January 2021

Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration

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7 January 2021

BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.

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7 January 2021

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

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7 January 2021

Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation

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7 January 2021

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

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7 January 2021

No Nogo: now where to go?

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7 January 2021

Mechanisms of axon ensheathment and myelin growth

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7 January 2021

Axonal neuregulin-1 regulates myelin sheath thickness

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7 January 2021

Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor

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7 January 2021

Neuregulin 1-erbB signaling is necessary for normal myelination and sensory function.

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7 January 2021

Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice

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7 January 2021

P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves

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7 January 2021

Evolution of a neuroprotective function of central nervous system myelin

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7 January 2021

Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination.

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7 January 2021

Neuregulin-1 type III determines the ensheathment fate of axons

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7 January 2021

Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitro

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7 January 2021

The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation.

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7 January 2021

Protein processing and releases of neuregulin-1 are regulated in an activity-dependent manner

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7 January 2021

Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival

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7 January 2021

Back signaling by the Nrg-1 intracellular domain

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7 January 2021

Release of the neuregulin functional polypeptide requires its cytoplasmic tail.

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7 January 2021

Identifiers

DOI

10.1038/NN1797

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15 May 2018

Dimensions Publication ID

1040504515

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15 May 2018