(Q53324159)

13 May 2018

title

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins. (English)

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13 May 2018

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De Strooper B

1

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13 May 2018

Beullens M

2

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13 May 2018

Contreras B

3

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13 May 2018

Levesque L

4

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13 May 2018

Craessaerts K

5

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13 May 2018

Cordell B

6

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13 May 2018

Moechars D

7

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13 May 2018

Bollen M

8

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13 May 2018

Fraser P

9

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13 May 2018

George-Hyslop PS

10

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13 May 2018

Van Leuven F

11

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13 May 2018

language of work or name

English

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publication date

1 February 1997

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13 May 2018

Journal of Biological Chemistry

published in

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13 May 2018

volume

272

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13 May 2018

issue

6

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13 May 2018

page(s)

3590-3598

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13 May 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

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The Alzheimer's disease sphinx: a riddle with plaques and tangles

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Apolipoprotein E and Alzheimer disease

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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Candidate gene for the chromosome 1 familial Alzheimer's disease locus

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Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3.

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

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Familial Alzheimer's chromosome 14 mutations

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Presenilins and Alzheimer disease

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Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

21 January 2018

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

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Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum

21 January 2018

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

21 January 2018

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Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

21 January 2018

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Preparation and characterisation of monoclonal and polyclonal antibodies to maize membrane auxin-binding protein

21 January 2018

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A C-terminal signal prevents secretion of luminal ER proteins

21 January 2018

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Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing

21 January 2018

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Immunohistochemical analysis of presenilin-1 expression in the mouse brain

21 January 2018

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S182 protein in Alzheimer's disease neuritic plaques.

21 January 2018

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Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

21 January 2018

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

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Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals

21 January 2018

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Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease

21 January 2018

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Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

21 January 2018

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Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation

21 January 2018

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Predicting the orientation of eukaryotic membrane-spanning proteins

21 January 2018

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The structure, role, and regulation of type 1 protein phosphatases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.6.3590

1 reference

13 May 2018

1 reference

13 May 2018