(Q52833166)

English

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.

scientific article published in February 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

G Benoit

2

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4 November 2019

M Flexor

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

J R Lillehaug

4

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Europe PubMed Central

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4 November 2019

M Lanotte

5

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4 November 2019

publication date

1 February 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673742%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

14

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Europe PubMed Central

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4 November 2019

2

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Europe PubMed Central

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4 November 2019

255-261

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4 November 2019

describes a project that uses

0 references

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

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Transgenic expression of PML/RARalpha impairs myelopoiesis

1 reference

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

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7 January 2021

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

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7 January 2021

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

1 reference

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7 January 2021

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Mutant AF-2 domain of PML-RARα in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARα and its down-regulation in acute promyelocytic leukemia

1 reference

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7 January 2021

based on heuristic

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Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line

1 reference

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7 January 2021

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Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction

1 reference

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7 January 2021

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Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

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7 January 2021

based on heuristic

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Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis

1 reference

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A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell

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Mutagenesis of the Ligand Binding Domain of the Human Retinoic Acid Receptor α Identifies Critical Residues for 9-cis-Retinoic Acid Binding

1 reference

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The nuclear receptor ligand-binding domain: structure and function

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A transcriptional co-repressor that interacts with nuclear hormone receptors

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Acute promyelocytic leukemia: a curable disease.

1 reference

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7 January 2021

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Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

1 reference

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RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

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based on heuristic

inferred from DOI database lookup

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