(Q52640776)

5 May 2018

title

Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development. (English)

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5 May 2018

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Eun-Suk Song

1

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5 May 2018

Maria Aparecida Juliano

series ordinal

2

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5 May 2018

Luiz Juliano

series ordinal

3

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5 May 2018

Louis B Hersh

series ordinal

4

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5 May 2018

language of work or name

English

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publication date

2 October 2003

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5 May 2018

Journal of Biological Chemistry

published in

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5 May 2018

volume

278

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5 May 2018

issue

50

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5 May 2018

page(s)

49789-49794

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5 May 2018

Insulin degradation: progress and potential

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Identification of gamma-endorphin-generating enzyme as insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Regulation of Insulin, Epidermal Growth Factor, and Transforming Growth Factor-α Levels by Growth Factor-Degrading Enzymes*

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Analysis of the subsite specificity of rat insulysin using fluorogenic peptide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

The use of proteolysis to study the structure of nardilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Degradation of amylin by insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

New fluorogenic substrates for N-arginine dibasic convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308983200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308983200

1 reference

5 May 2018

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5 May 2018