(Q52538228)

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Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons.

scientific article published in February 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10700549%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons (English)

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Europe PubMed Central

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4 November 2019

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4 November 2019

Tadeusz Wieloch

4

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4 November 2019

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A Petersén

1

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4 November 2019

R F Castilho

2

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4 November 2019

P Brundin

5

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4 November 2019

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1 February 2000

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4 November 2019

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10

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4 November 2019

857

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4 November 2019

1-2

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4 November 2019

20-29

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4 November 2019

Alternative excitotoxic hypotheses

1 reference

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Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

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Mitochondrial dysfunction in neurodegenerative diseases

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Growth of a rat neuroblastoma cell line in serum-free supplemented medium

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Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

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Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

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Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria

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Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells.

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Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid-Induced Brain Swelling

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Calcium ionophore-induced degradation of neurofilament and cell death in MSN neuroblastoma cells

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Excitotoxic cell death

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Oxidative stress, glutamate, and neurodegenerative disorders

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Manganic Porphyrins Possess Catalase Activity and Protect Endothelial Cells against Hydrogen Peroxide-Mediated Injury

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The Role of CED-3-Related Cysteine Proteases in Apoptosis of Cerebellar Granule Cells

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7 January 2021

Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress

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7 January 2021

Mitochondria and apoptosis

1 reference

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7 January 2021

Mitochondrial defect in Huntington's disease caudate nucleus

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7 January 2021

Mechanisms by which mitochondria transport calcium

1 reference

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7 January 2021

Calcium ionophores can induce either apoptosis or necrosis in cultured cortical neurons

1 reference

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7 January 2021

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

1 reference

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7 January 2021

A role of peroxides in Ca2+ ionophore-induced apoptosis in cultured rat cortical neurons

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7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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7 January 2021

Neuronal death, cytoplasmic calcium and internucleosomal DNA fragmentation: evidence for DNA fragments being released from cells

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7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

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7 January 2021

Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

1 reference

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7 January 2021

NMDA-dependent superoxide production and neurotoxicity

1 reference

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7 January 2021

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

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7 January 2021

Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro

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7 January 2021

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

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7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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7 January 2021

Evidence for calcium-reducing and excitoprotective roles for the calcium-binding protein calbindin-1328k in cultured hippocampal neurons

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7 January 2021

Morphological and molecular characterization of the response of differentiated PC12 cells to calcium stress

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Antioxidant treatment protects striatal neurons against excitotoxic insults

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Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187-induced cell death in cultured embryonic striatal neurons

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Recent advances on the pathogenesis of Huntington's disease

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Neuronal cell death

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Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

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Biological applications of ionophores

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The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.

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Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

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Calcium Dependence of Toxic Cell Death: A Final Common Pathway

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Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.

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Apoptotic Cell Death and Caspase 3 (CPP32) Activation Induced by Calcium Ionophore at Low Concentrations and their Prevention by Nerve Growth Factor in PC12 Cells

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Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

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Huntington disease

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Oxidative stress in Huntington's disease

1 reference

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based on heuristic

inferred from DOI database lookup

Calcium and neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2902320-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0006-8993(99)02320-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10700549%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10700549%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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