(Q51985324)

19 April 2018

title

Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione (English)

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19 April 2018

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1

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Roberto Cappai

5

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19 April 2018

author name string

Bush AI

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19 April 2018

Beyreuther K

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Masters CL

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language of work or name

English

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publication date

1 May 1999

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19 April 2018

Journal of Neurochemistry

published in

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volume

72

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issue

5

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19 April 2018

page(s)

2092-2098

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19 April 2018

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

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Promotion of transition metal-induced reactive oxygen species formation by beta-amyloid

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Oxidative damage to proteins and lipids of CNS myelin produced by in vitro generated reactive oxygen species

21 January 2018

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The cellular prion protein binds copper in vivo

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Oxidative stress in a clonal cell line of neuronal origin: effects of antioxidant enzyme modulation

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Oxidative stress after acute and chronic application of beta-amyloid fragment 25-35 in cortical cultures

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Copper(I) transfer into metallothionein mediated by glutathione

21 January 2018

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The beta A4 amyloid precursor protein binding to copper.

21 January 2018

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Copper ions differ from other thiol reactive metal ions in their effects on the concentration and redox status of thiols in HeLa cell cultures

21 January 2018

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Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

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Glutathione is involved in the early cadmium cytotoxic response in human lung carcinoma cells

21 January 2018

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Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability

21 January 2018

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Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

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Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease

21 January 2018

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Copper, iron and zinc in Alzheimer's disease senile plaques

21 January 2018

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The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

21 January 2018

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Free radicals in medicine. II. Involvement in human disease

21 January 2018

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Cellular copper transport

21 January 2018

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Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

21 January 2018

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A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

21 January 2018

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A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

21 January 2018

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Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis

21 January 2018

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10.1046/J.1471-4159.1999.0722092.X

21 January 2018

Identifiers

DOI

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19 April 2018

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19 April 2018