(Q51006407)

26 March 2018

title

Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets (English)

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26 March 2018

author

Jean-Christophe Jonas

7

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author name string

H Elouil

1

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M Bensellam

2

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Y Guiot

3

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D Vander Mierde

4

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S M A Pascal

5

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F C Schuit

6

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publication date

12 May 2007

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26 March 2018

published in

Diabetologia

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26 March 2018

volume

50

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issue

7

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page(s)

1442-1452

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26 March 2018

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

cites work

1 reference

12 December 2020

Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets

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12 December 2020

High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells

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12 December 2020

Glucose-sensing mechanisms in pancreatic beta-cells.

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12 December 2020

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

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12 December 2020

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

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12 December 2020

The mammalian unfolded protein response

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12 December 2020

Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells.

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12 December 2020

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

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12 December 2020

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

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12 December 2020

Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells

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12 December 2020

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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12 December 2020

Role for activating transcription factor 3 in stress-induced beta-cell apoptosis

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12 December 2020

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

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12 December 2020

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

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12 December 2020

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

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12 December 2020

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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12 December 2020

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

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12 December 2020

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

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12 December 2020

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

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12 December 2020

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

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12 December 2020

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

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12 December 2020

Endoplasmic reticulum stress signaling in disease

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12 December 2020

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

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12 December 2020

ER chaperone functions during normal and stress conditions

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12 December 2020

The effect of sugars on (pro)insulin biosynthesis

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12 December 2020

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

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12 December 2020

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB.

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12 December 2020

GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress

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12 December 2020

Respiratory, ionic, and functional effects of succinate esters in pancreatic islets.

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12 December 2020

Chaperone-mediated protein folding

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12 December 2020

Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.

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12 December 2020

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

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12 December 2020

Determination of total serum insulin (IRI) in insulin-treated diabetic patients

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12 December 2020

ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity

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12 December 2020

Differences in adrenergic recognition by pancreatic A and B cells

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12 December 2020

Distinct glucose-dependent stress responses revealed by translational profiling in pancreatic beta-cells.

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12 December 2020

Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal

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12 December 2020

The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine

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12 December 2020

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

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12 December 2020

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP.

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12 December 2020

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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12 December 2020

Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose

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12 December 2020

Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.

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12 December 2020

Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways

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12 December 2020

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

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12 December 2020

10.1007/S00125-007-0674-4

Identifiers

DOI

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26 March 2018

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26 March 2018