(Q50436260)

14 March 2018

title

Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation (English)

1 reference

14 March 2018

main subject

chronic myeloid leukemia

0 references

1 reference

1 reference

1

Yusuf Baran

1 reference

14 March 2018

4

Besim Ogretmen

1 reference

14 March 2018

author name string

Jacek Bielawski

series ordinal

2

1 reference

14 March 2018

Ufuk Gunduz

series ordinal

3

1 reference

14 March 2018

publication date

11 August 2011

1 reference

14 March 2018

Journal of Cancer Research and Clinical Oncology

published in

1 reference

14 March 2018

volume

137

1 reference

14 March 2018

issue

10

1 reference

14 March 2018

page(s)

1535-1544

1 reference

14 March 2018

Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

p53-dependent ceramide response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Functions of ceramide in coordinating cellular responses to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Differential expression of sphingolipids in MRP1 overexpressing HT29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Regulation of ceramide production and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Mechanisms of resistance to imatinib (STI571) and prospects for combination with conventional chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Glucosylceramide synthetase inhibitor, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol exhibits a novel decarcinogenic activity against Shope carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Glucosylceramides stimulate murine epidermal hyperproliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Paclitaxel-induced apoptosis in Jurkat, a leukemic T cell line, is enhanced by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Biologically active sphingolipids in cancer pathogenesis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Novel targeted therapies to overcome imatinib mesylate resistance in chronic myeloid leukemia (CML).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-011-1016-Y

Inhibition of experimental metastasis of murine Lewis lung carcinoma by an inhibitor of glucosylceramide synthase and its possible mechanism of action

21 January 2018

1 reference

12 December 2020

Apoptosis: molecular regulation of cell death

1 reference

12 December 2020

Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance.

1 reference

12 December 2020

Non-Hodgkin's lymphoma associated with Gaucher's disease

1 reference

12 December 2020

Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

1 reference

12 December 2020

Glucosylceramide: a marker for multiple-drug resistant cancers

1 reference

12 December 2020

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells

1 reference

12 December 2020

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

1 reference

12 December 2020

Synergistic effect of imatinib mesylate and fludarabine combination on Philadelphia chromosome-positive chronic myeloid leukemia cell lines

1 reference

12 December 2020

1-phenyl-2-decanoylamino-3-morpholino-1-propanol chemosensitizes neuroblastoma cells for taxol and vincristine.

1 reference

12 December 2020

Imatinib mesylate and the management of chronic myeloid leukemia (CML)

1 reference

12 December 2020

SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells

1 reference

12 December 2020

Apoptosis induced by N-hexanoylsphingosine in CHP-100 cells associates with accumulation of endogenous ceramide and is potentiated by inhibition of glucocerebroside synthesis

1 reference

12 December 2020

Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance.

1 reference

12 December 2020

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

1 reference

12 December 2020

Resistance to imatinib: mechanisms and management

1 reference

12 December 2020

Diversity and complexity of ceramide signalling in apoptosis

1 reference

12 December 2020

10.1007/S00432-011-1016-Y

Identifiers

DOI

1 reference

14 March 2018

1 reference

14 March 2018