(Q48970037)

17 February 2018

title

Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis (English)

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17 February 2018

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Z F Yu

1

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17 February 2018

M Nikolova-Karakashian

2

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17 February 2018

D Zhou

3

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17 February 2018

G Cheng

4

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17 February 2018

E H Schuchman

5

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17 February 2018

M P Mattson

6

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17 February 2018

publication date

1 October 2000

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17 February 2018

Journal of Molecular Neuroscience

published in

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17 February 2018

volume

15

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17 February 2018

issue

2

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17 February 2018

page(s)

85-97

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17 February 2018

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation

cites work

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12 December 2020

Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes

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12 December 2020

Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury

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12 December 2020

Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death

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12 December 2020

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

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12 December 2020

FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

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12 December 2020

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

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12 December 2020

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

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12 December 2020

PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway

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12 December 2020

The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy

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12 December 2020

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

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12 December 2020

Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes

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12 December 2020

Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity

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12 December 2020

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury

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12 December 2020

Neuroprotective signal transduction: relevance to stroke

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12 December 2020

Pathobiology of ischaemic stroke: an integrated view

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12 December 2020

Dexamethasone-induced thymocyte apoptosis: apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases

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12 December 2020

Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells

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12 December 2020

Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

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12 December 2020

Ceramide in apoptosis--does it really matter?

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12 December 2020

Reduced Ischemic Brain Injury in Interleukin-1β Converting Enzyme—Deficient Mice

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12 December 2020

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12 December 2020

Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes.

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12 December 2020

Ceramide and cyclic adenosine monophosphate (cAMP) induce cAMP response element binding protein phosphorylation via distinct signaling pathways while having opposite effects on myeloid cell survival.

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12 December 2020

Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappaB/JNK kinase and cell survival

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12 December 2020

Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat

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12 December 2020

Quantitation of free sphingosine in liver by high-performance liquid chromatography

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12 December 2020

Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease

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12 December 2020

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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12 December 2020

Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide-induced apoptosis

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12 December 2020

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

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12 December 2020

Bimodal regulation of ceramidase by interleukin-1beta. Implications for the regulation of cytochrome p450 2C11.

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12 December 2020

Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease.

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12 December 2020

Ceramide induces apoptosis in PC12 cells

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12 December 2020

Oxidative stress in brain ischemia.

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12 December 2020

Ceramide induces apoptosis in cultured mesencephalic neurons

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12 December 2020

Cerebral Interleukin-6 is Neuroprotective during Permanent Focal Cerebral Ischemia in the Rat

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12 December 2020

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

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12 December 2020

Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

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12 December 2020

Signal transduction of stress via ceramide

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12 December 2020

Ceramide triggers intracellular calcium release via the IP(3) receptor in Xenopus laevis oocytes

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12 December 2020

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

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12 December 2020

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein

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12 December 2020

Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor

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12 December 2020

Accumulation of ceramide in ischemic human brain of an acute case of cerebral occlusion

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12 December 2020

Ceramide and the eukaryotic stress response

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12 December 2020

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

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12 December 2020

Neuroprotective effects of gelsolin during murine stroke

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12 December 2020

Role of colony stimulating factor-1 in brain damage caused by ischemia

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12 December 2020

Ceramide signalling and the immune response

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12 December 2020

Identifiers

DOI

10.1385/JMN:15:2:85

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17 February 2018

Dimensions Publication ID

1049778396

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17 February 2018