(Q48950667)

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Key Amino Acids in the γ Subunit of the γ-Aminobutyric AcidAReceptor that Determine Ligand Binding and Modulation at the Benzodiazepine Site

scientific article published on November 1, 1997

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Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

Key amino acids in the gamma subunit of the gamma-aminobutyric acidA receptor that determine ligand binding and modulation at the benzodiazepine site (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

Key Amino Acids in the γ Subunit of the γ-Aminobutyric AcidAReceptor that Determine Ligand Binding and Modulation at the Benzodiazepine Site (English)

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

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inferred from title

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P. J. Whiting

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9351978

21 November 2024

author name string

P. B. Wingrove

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9351978

21 November 2024

S. A. Thompson

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9351978

21 November 2024

K. A. Wafford

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9351978

21 November 2024

language of work or name

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9351978

21 November 2024

publication date

1 November 1997

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

November 1997

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9351978

21 November 2024

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/mol.52.5.874

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Molecular Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

52

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

5

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

874-881

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

Which GABAA-receptor subtypes really occur in the brain?

2

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

3

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published]

4

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Stoichiometry of a recombinant GABAA receptor.

6

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

8

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Type I and type II GABAA-benzodiazepine receptors produced in transfected cells

9

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

11

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site

13

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

The pharmacology of the benzodiazepine site of the GABA-A receptor is dependent on the type of gamma-subunit present

16

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

The major site of photoaffinity labeling of the gamma-aminobutyric acid type A receptor by [3H]flunitrazepam is histidine 102 of the alpha subunit.

17

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Expression and pharmacology of human GABAA receptors containing gamma 3 subunits

21

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

GABAA receptor subtypes differentiated by their gamma-subunit variants: prevalence, pharmacology and subunit architecture

22

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

23

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.

24

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

26

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

28

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital

30

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Two tyrosine residues on the alpha subunit are crucial for benzodiazepine binding and allosteric modulation of gamma-aminobutyric acidA receptors

31

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA.

33

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins

34

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site

35

1 reference

10.1124/MOL.52.5.874

https://api.crossref.org/works/10.1124/MOL.52.5.874

21 November 2024

Identifiers

10.1124/MOL.52.5.874

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/9351978

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