(Q47817716)

5 February 2018

title

IL-6 is required for glioma development in a mouse model (English)

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5 February 2018

author

Manfred Kopf

4

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5 February 2018

Adriano Aguzzi

7

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5 February 2018

author name string

Jakob Weissenberger

1

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5 February 2018

Sébastien Loeffler

2

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5 February 2018

Andreas Kappeler

3

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5 February 2018

Anton Lukes

5

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5 February 2018

Tatiana A Afanasieva

6

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5 February 2018

Joachim Weis

8

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5 February 2018

language of work or name

English

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publication date

1 April 2004

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5 February 2018

published in

Oncogene

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5 February 2018

volume

23

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5 February 2018

issue

19

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5 February 2018

page(s)

3308-3316

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5 February 2018

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

cites work

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SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

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Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

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Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

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Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways

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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

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Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

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Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

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Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3

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7 January 2021

Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

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7 January 2021

Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice

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7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207455

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5 February 2018

Dimensions Publication ID

1034766609

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1 reference

5 February 2018