(Q47764326)

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Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

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Europe PubMed Central

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5 February 2018

http://europepmc.org/abstract/MED/19455118

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease (English)

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5 February 2018

http://europepmc.org/abstract/MED/19455118

ulcerative colitis

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Joerg T. Epplen

7

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5 February 2018

http://europepmc.org/abstract/MED/19455118

Bertram Müller-Myhsok

16

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Bertram Müller-Myhsok

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http://europepmc.org/abstract/MED/19455118

3

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Stephan Ripke

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Jürgen Glas

1

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http://europepmc.org/abstract/MED/19455118

Johannes Stallhofer

2

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http://europepmc.org/abstract/MED/19455118

Martin Wetzke

4

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Simone Pfennig

5

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Wolfram Klein

6

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http://europepmc.org/abstract/MED/19455118

Thomas Griga

8

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Uwe Schiemann

9

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http://europepmc.org/abstract/MED/19455118

Martin Lacher

10

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Sibylle Koletzko

11

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Matthias Folwaczny

12

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Peter Lohse

13

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Burkhard Göke

14

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Thomas Ochsenkühn

15

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Stephan Brand

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publication date

19 May 2009

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The American Journal of Gastroenterology

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104

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7

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1737-1744

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Inflammatory Bowel Disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Unravelling the pathogenesis of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Genetic variation in myosin IXB is associated with ulcerative colitis

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Inflammatory bowel disease in patients with celiac disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Claudins regulate the intestinal barrier in response to immune mediators

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Regulation of gut inflammation and th17 cell response by interleukin-21.

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Interleukin 21 as a target of intervention in autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.163

21 January 2018

Identifiers

10.1038/AJG.2009.163

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/19455118

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/19455118

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