(Q47714048)

5 February 2018

title

Alpha-2 macroglobulin is genetically associated with Alzheimer disease (English)

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11

Albert MS

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author name string

Blacker D

1

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Wilcox MA

2

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Laird NM

3

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Rodes L

4

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Horvath SM

5

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Go RC

6

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Perry R

7

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Watson B Jr

8

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Bassett SS

9

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McInnis MG

10

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Hyman BT

12

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Tanzi RE

13

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language of work or name

English

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publication date

1 August 1998

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published in

Nature Genetics

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volume

19

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issue

4

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page(s)

357-360

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The genetics of Alzheimer disease: current status and future prospects

cites work

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7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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7 January 2021

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

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7 January 2021

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

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7 January 2021

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), and apolipoprotein E receptor, with late-onset Alzheimer's disease

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7 January 2021

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7 January 2021

Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells

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7 January 2021

Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein.

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7 January 2021

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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7 January 2021

Alpha2-macroglobulin attenuates beta-amyloid peptide 1-40 fibril formation and associated neurotoxicity of cultured fetal rat cortical neurons.

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7 January 2021

Degradation of amyloid beta-protein by a serine protease-alpha2-macroglobulin complex

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7 January 2021

Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

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7 January 2021

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

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7 January 2021

A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene

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7 January 2021

A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test

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7 January 2021

Genetic studies on chromosome 12 in late-onset Alzheimer disease.

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7 January 2021

APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease

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7 January 2021

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

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7 January 2021

A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease.

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7 January 2021

Distortion of allelic expression of apolipoprotein E in Alzheimer's disease.

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7 January 2021

Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

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7 January 2021

Reliability and Validity of NINCDS-ADRDA Criteria for Alzheimer's Disease

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7 January 2021

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

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7 January 2021

Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity.

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7 January 2021

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

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7 January 2021

Identifiers

DOI

10.1038/1243

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5 February 2018

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5 February 2018