(Q47692442)

4 February 2018

title

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments (English)

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4 February 2018

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Saccharomyces cerevisiae

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2

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4 February 2018

author name string

Shusta EV

series ordinal

1

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4 February 2018

Plückthun A

series ordinal

3

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4 February 2018

Wittrup KD

series ordinal

4

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4 February 2018

publication date

1 August 1998

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4 February 2018

published in

Nature Biotechnology

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4 February 2018

volume

16

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4 February 2018

issue

8

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4 February 2018

page(s)

773-777

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4 February 2018

Effects of co-expressing chaperone BiP on functional antibody production in the baculovirus system

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1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

Quality control in the secretory pathway

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Expression level tuning for optimal heterologous protein secretion in Saccharomyces cerevisiae.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Protein Disulfide Isomerase and Assisted Protein Folding

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Catalysis of oxidative protein folding by mutants of protein disulfide isomerase with a single active-site cysteine

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Overexpression of binding protein and disruption of the PMR1 gene synergistically stimulate secretion of bovine prochymosin but not plant thaumatin in yeast.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Coexpression of molecular chaperone BiP improves immunoglobulin solubility and IgG secretion from Trichoplusia ni insect cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Protein disulfide isomerase mutant lacking its isomerase activity accelerates protein folding in the cell.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Protein folding in the cell

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

Monoclonal antibody-based therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Characterization and applications of antibodies produced in plants

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Engineered turns of a recombinant antibody improve its in vivo folding

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Secretion of functional antibody and Fab fragment from yeast cells

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

The synthesis and in vivo assembly of functional antibodies in yeast.

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Review: methylotrophic yeasts as factories for the production of foreign proteins

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

An integrating vector for tunable, high copy, stable integration into the dispersed Ty delta sites of Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Constitutive overexpression of secreted heterologous proteins decreases extractable BiP and protein disulfide isomerase levels in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Regulated GAL4 expression cassette providing controllable and high-level output from high-copy galactose promoters in yeast

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

A comparison of strategies to stabilize immunoglobulin Fv-fragments

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Association of transport-defective light chains with immunoglobulin heavy chain binding protein

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https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Using Molecular Genetics to Improve the Production of Recombinant Proteins by the Yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

The disulfide bonds in antibody variable domains: effects on stability, folding in vitro, and functional expression in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Functional antibody production using cell-free translation: effects of protein disulfide isomerase and chaperones.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Multicopy overexpression of bovine pancreatic trypsin inhibitor saturates the protein folding and secretory capacity of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNBT0898-773

7 January 2021

Identifiers

DOI

10.1038/NBT0898-773

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4 February 2018

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4 February 2018