(Q47367409)

English

Bridging structural biology and genetics by computational methods: an investigation into how the R774C mutation in the AR gene can result in complete androgen insensitivity syndrome

scientific article published in December 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Bridging structural biology and genetics by computational methods: an investigation into how the R774C mutation in the AR gene can result in complete androgen insensitivity syndrome (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

complete androgen insensitivity syndrome

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structural biology

1 reference

based on heuristic

inferred from title

Lenore K Beitel

6

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

author name string

Jian Hui Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Bruce Gottlieb

2

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Gerald Batist

3

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Traian Sulea

4

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Enrico O Purisima

5

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Mark Trifiro

7

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

publication date

1 December 2003

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Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

22

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

6

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

465-475

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

Simulations of the molecular dynamics of nucleic acids

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Functional characterization of naturally occurring mutant androgen receptors from subjects with complete androgen insensitivity

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Continuum solvent molecular dynamics study of flexibility in interleukin-8

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A novel mutation (N233K) in the transactivating domain and the N756S mutation in the ligand binding domain of the androgen receptor gene are associated with male infertility

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A novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production

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Clinical and molecular spectrum of somatic mosaicism in androgen insensitivity syndrome

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Single amino acid substitution (840Arg-->His) in the hormone-binding domain of the androgen receptor leads to incomplete androgen insensitivity syndrome associated with a thermolabile androgen receptor

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Molecular dynamics simulations of biomolecules

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Androgen receptor defects in patients with minimal and partial androgen resistance classified according to a model of androgen-receptor complex energy states

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Molecular analysis of the androgen receptor gene in 4 patients with complete androgen insensitivity

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Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations

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Recent developments in computational proteomics

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Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

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Absolute comparison of simulated and experimental protein-folding dynamics

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Binding of ligands and activation of transcription by nuclear receptors.

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Theory and applications of the generalized Born solvation model in macromolecular simulations

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Solvent mobility and the protein 'glass' transition

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Partial androgen insensitivity and correlations with the predicted three dimensional structure of the androgen receptor ligand-binding domain.

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Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

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Identifiers

10.1002/HUMU.10279

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 January 2018

http://europepmc.org/abstract/MED/14635106

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