(Q47221910)

12 January 2018

title

B cell receptor signal strength determines B cell fate (English)

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12 January 2018

author

Klaus Rajewsky

8

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author name string

Stefano Casola

1

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12 January 2018

Kevin L Otipoby

2

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12 January 2018

Marat Alimzhanov

3

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12 January 2018

Sibille Humme

4

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12 January 2018

Nathalie Uyttersprot

5

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12 January 2018

Jeffery L Kutok

6

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12 January 2018

Michael C Carroll

7

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language of work or name

English

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publication date

1 February 2004

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12 January 2018

published in

Nature Immunology

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12 January 2018

volume

5

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issue

3

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12 January 2018

page(s)

317-327

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12 January 2018

Origins and functions of B-1 cells with notes on the role of CD5

cites work

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Clonal selection and learning in the antibody system

21 January 2018

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21 January 2018

Marginal-zone B cells

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Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow

21 January 2018

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Monomeric and oligomeric complexes of the B cell antigen receptor

21 January 2018

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The peritoneal Ly-1 (CD5) B cell repertoire is unique among murine B cell repertoires

21 January 2018

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Antigen-dependent B-cell development

21 January 2018

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Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis

21 January 2018

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21 January 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

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B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development.

21 January 2018

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Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment

21 January 2018

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Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail

21 January 2018

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Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

21 January 2018

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Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR.

21 January 2018

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Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module

21 January 2018

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Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases

21 January 2018

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The Immunoreceptor Tyrosine-Based Activation Motif of Epstein–Barr Virus LMP2A Is Essential for Blocking BCR-Mediated Signal Transduction

21 January 2018

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The preference for switching to expression of the IgA isotype of antibody exhibited by B lymphocytes in Peyer's patches is likely due to intrinsic properties of their microenvironment

21 January 2018

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The role of complement and complement receptors in induction and regulation of immunity.

21 January 2018

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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

21 January 2018

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

21 January 2018

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In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

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The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo

21 January 2018

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B-1 cell development: evidence for an uncommitted immunoglobulin (Ig)M+ B cell precursor in B-1 cell differentiation

21 January 2018

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Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development

21 January 2018

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Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.

21 January 2018

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Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.

21 January 2018

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Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses

21 January 2018

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Integrin-mediated long-term B cell retention in the splenic marginal zone.

21 January 2018

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Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

21 January 2018

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Itchy, a Nedd4 Ubiquitin Ligase, Downregulates Latent Membrane Protein 2A Activity in B-Cell Signaling

21 January 2018

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Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development

21 January 2018

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The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Complement. First of two parts

21 January 2018

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Collaboration of epithelial cells with organized mucosal lymphoid tissues.

21 January 2018

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Dendritic cells shuttle microbes across gut epithelial monolayers

21 January 2018

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Lymph node germinal centers form in the absence of follicular dendritic cell networks

21 January 2018

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A hyperconversion mechanism generates the chicken light chain preimmune repertoire

21 January 2018

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Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches

21 January 2018

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A new model of sheep Ig diversification: shifting the emphasis toward combinatorial mechanisms and away from hypermutation

21 January 2018

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CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

21 January 2018

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THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

21 January 2018

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Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

21 January 2018

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B cell development under the condition of allelic inclusion.

21 January 2018

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

21 January 2018

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Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

21 January 2018

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A Prematurely Expressed Igκ Transgene, but Not a VκJκ Gene Segment Targeted into the Igκ Locus, Can Rescue B Cell Development in λ5-Deficient Mice

21 January 2018

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Positive selection of natural autoreactive B cells

21 January 2018

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7 January 2021

Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

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7 January 2021

Ontogeny, distribution and function of CD38-expressing B lymphocytes in mice

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7 January 2021

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

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7 January 2021

Manipulation of transgenes by site-specific recombination: use of Cre recombinase

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7 January 2021

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

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7 January 2021

Identifiers

DOI

10.1038/NI1036

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12 January 2018

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12 January 2018