(Q46986551)

27 December 2017

title

SorLA signaling by regulated intramembrane proteolysis (English)

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27 December 2017

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5

Christian Haass

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author name string

Christopher Böhm

1

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27 December 2017

Nicole M Seibel

2

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27 December 2017

Birgit Henkel

3

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27 December 2017

Harald Steiner

4

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27 December 2017

Wolfgang Hampe

6

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27 December 2017

language of work or name

English

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publication date

10 March 2006

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27 December 2017

Journal of Biological Chemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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27 December 2017

volume

281

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27 December 2017

issue

21

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27 December 2017

page(s)

14547-14553

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27 December 2017

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

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Gamma-secretase: proteasome of the membrane?

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RIPped out by presenilin-dependent gamma-secretase

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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

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Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide

21 January 2018

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gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

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Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

21 January 2018

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Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration

21 January 2018

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Mechanism and biological significance of CD44 cleavage

21 January 2018

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Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

21 January 2018

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Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member

21 January 2018

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Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex

21 January 2018

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Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

21 January 2018

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The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

21 January 2018

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Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line

21 January 2018

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Neurotensin receptor-3/sortilin mediates neurotensin-induced cytokine/chemokine expression in a murine microglial cell line

21 January 2018

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The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.

21 January 2018

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Functional organization of the sortilin Vps10p domain

21 January 2018

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The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

21 January 2018

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LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro

21 January 2018

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LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration

21 January 2018

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Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

21 January 2018

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The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments

21 January 2018

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Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

21 January 2018

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Loss of apolipoprotein E receptor LR11 in Alzheimer disease

21 January 2018

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A proteomic approach for the identification of cell-surface proteins shed by metalloproteases

21 January 2018

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

21 January 2018

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NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell

21 January 2018

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Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data

21 January 2018

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Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis

21 January 2018

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Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

21 January 2018

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes

21 January 2018

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Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

21 January 2018

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Expression of LR11, a mosaic LDL receptor family member, is markedly increased in atherosclerotic lesions

21 January 2018

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Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae

21 January 2018

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Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.

21 January 2018

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Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601660200

Low density lipoprotein receptor-related protein (LRP) interacts with presenilin 1 and is a competitive substrate of the amyloid precursor protein (APP) for gamma-secretase

21 January 2018

1 reference

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

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Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

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Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601660200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601660200

1 reference

27 December 2017

1 reference

27 December 2017