(Q46959086)

26 December 2017

title

Drug-induced liver injury: summary of a single topic clinical research conference (English)

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26 December 2017

author name string

Paul B Watkins

series ordinal

1

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26 December 2017

Leonard B Seeff

series ordinal

2

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26 December 2017

language of work or name

English

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publication date

1 March 2006

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26 December 2017

published in

Hepatology

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26 December 2017

volume

43

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26 December 2017

issue

3

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26 December 2017

page(s)

618-631

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26 December 2017

Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States

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Embolization by sinusoidal lining cells obstructs the microcirculation in rat sinusoidal obstruction syndrome

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Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year Period

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Drug-induced hepatotoxicity.

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Surveillance for fatal suspected adverse drug reactions in the UK

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7 January 2021

Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants

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7 January 2021

Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites

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7 January 2021

Anticonvulsant hypersensitivity syndrome: incidence, prevention and management

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7 January 2021

Valproate-induced liver failure in one of two siblings with Alpers disease

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7 January 2021

Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity

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7 January 2021

Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis

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7 January 2021

The role of metabolic activation in drug-induced hepatotoxicity

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7 January 2021

Role of metabolism in drug-induced idiosyncratic hepatotoxicity

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7 January 2021

Drug-protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development

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7 January 2021

Elucidating mechanisms of drug-induced toxicity.

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7 January 2021

Platelet phenol sulfotransferase activity: correlation with sulfate conjugation of acetaminophen

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7 January 2021

Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters

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7 January 2021

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

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7 January 2021

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

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7 January 2021

Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats

1 reference

7 January 2021

Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats

1 reference

7 January 2021

Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine

1 reference

7 January 2021

Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine

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7 January 2021

Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor

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7 January 2021

Idiosyncratic drug hepatotoxicity

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7 January 2021

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

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7 January 2021

A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury.

1 reference

7 January 2021

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

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7 January 2021

Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase

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7 January 2021

Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease

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7 January 2021

Drug-induced lupus-like syndrome associated with severe autoimmune hepatitis

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7 January 2021

Autoimmune hepatitis revealed by atorvastatin

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7 January 2021

Rosuvastatin-associated hepatitis with autoimmune features

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7 January 2021

Drug-induced immunotoxicity

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7 January 2021

Drug-induced cholestasis

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7 January 2021

Drug- and chemical-induced cholestasis

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7 January 2021

Vanishing bile duct syndrome in drug-induced liver disease

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7 January 2021

Drug-induced prolonged cholestasis in adults: A histological semiquantitative study demonstrating progressive ductopenia

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7 January 2021

Molecular pathogenesis of cholestasis.

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7 January 2021

Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions

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7 January 2021

Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2)

1 reference

7 January 2021

Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats

1 reference

7 January 2021

Hepatic MRI for fat quantitation: its relationship to fat morphology, diagnosis, and ultrasound

1 reference

7 January 2021

Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

1 reference

7 January 2021

Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice.

1 reference

7 January 2021

Mitochondrial toxicity of antiviral drugs

1 reference

7 January 2021

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes

1 reference

7 January 2021

Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease).

1 reference

7 January 2021

Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells

1 reference

7 January 2021

Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition

1 reference

7 January 2021

Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells

1 reference

7 January 2021

Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro

1 reference

7 January 2021

Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome

1 reference

7 January 2021

Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.

1 reference

7 January 2021

Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury

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7 January 2021

Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride

1 reference

7 January 2021

Interleukin-6 regulates hepatic transporters during acute-phase response

1 reference

7 January 2021

Hepatotoxicity of antiretrovirals: incidence, mechanisms and management

1 reference

7 January 2021

Antiretroviral-associated liver injury

1 reference

7 January 2021

Severe hepatotoxicity during combination antiretroviral treatment: incidence, liver histology, and outcome

1 reference

7 January 2021

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

1 reference

7 January 2021

Metabonomics and its role in drug development and disease diagnosis

1 reference

7 January 2021

Metabonomics: a platform for studying drug toxicity and gene function

1 reference

7 January 2021

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

1 reference

7 January 2021

NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats

1 reference

7 January 2021

Gut microorganisms, mammalian metabolism and personalized health care

1 reference

7 January 2021

Drug-induced liver injury: mechanisms and test systems.

1 reference

7 January 2021

Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis

1 reference

7 January 2021

Comparison of two clinical scales for causality assessment in hepatotoxicity

1 reference

7 January 2021

Clinical diagnostic scale: a useful tool in the evaluation of suspected hepatotoxic adverse drug reactions.

1 reference

7 January 2021

Causality assessment of adverse drug reactions: comparison of the results obtained from published decisional algorithms and from the evaluations of an expert panel, according to different levels of imputability.

1 reference

7 January 2021

1 reference

7 January 2021

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

1 reference

7 January 2021

Assessment of hepatotoxic liabilities by transcript profiling

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7 January 2021

Drug metabolizing enzymes in lymphocytes

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7 January 2021

Identifiers

DOI

10.1002/HEP.21095

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26 December 2017

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26 December 2017