(Q46505377)

22 December 2017

title

Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia (English)

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22 December 2017

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Viviane Labrie

1

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22 December 2017

Tatiana Lipina

series ordinal

2

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22 December 2017

John C Roder

series ordinal

3

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22 December 2017

publication date

3 July 2008

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22 December 2017

number of pages

14

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inferred from page(s)

published in

Psychopharmacology

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22 December 2017

volume

200

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22 December 2017

issue

2

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22 December 2017

page(s)

217-230

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22 December 2017

Cognitive function in schizophrenia: association with negative and positive symptoms

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Animal models for the negative symptoms of schizophrenia

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

21 January 2018

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Recent advances in the phencyclidine model of schizophrenia

21 January 2018

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Repeated administration of phencyclidine, amphetamine and MK-801 selectively impairs spatial learning in mice: a possible model of psychotomimetic drug-induced cognitive deficits

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12 December 2020

Effects of site-selective NMDA receptor antagonists in an elevated plus-maze model of anxiety in mice

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12 December 2020

First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients

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12 December 2020

The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

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12 December 2020

The pharmacology of latent inhibition as an animal model of schizophrenia

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12 December 2020

Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1.

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12 December 2020

Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice

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12 December 2020

ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter

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12 December 2020

D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning

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12 December 2020

Clinical features of latent inhibition in schizophrenia

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12 December 2020

Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia.

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Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala.

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Neurobiology of schizophrenia

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12 December 2020

Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

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12 December 2020

Mobile NMDA receptors at hippocampal synapses

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12 December 2020

Evaluation of the NR2B-selective NMDA receptor antagonist Ro 63-1908 on rodent behaviour: evidence for an involvement of NR2B NMDA receptors in response inhibition

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12 December 2020

Glycine binding primes NMDA receptor internalization

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12 December 2020

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

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12 December 2020

Polymorphism in the 5'-promoter region of serine racemase gene in schizophrenia

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12 December 2020

N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives

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12 December 2020

Early auditory sensory processing deficits in mouse mutants with reduced NMDA receptor function

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12 December 2020

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

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12 December 2020

Hippocampal damage and exploratory preferences in rats: memory for objects, places, and contexts

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12 December 2020

Differential relationships between positive and negative symptoms and neuropsychological deficits in schizophrenia

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12 December 2020

Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function

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12 December 2020

Phencyclidine-induced stereotyped behaviour and social isolation in rats: a possible animal model of schizophrenia.

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12 December 2020

Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function

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Vasopressin V1b receptor knockout reduces aggressive behavior in male mice

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12 December 2020

NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity

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N‐methyl‐d‐aspartate receptor NR1 subunit gene (GRIN1) in schizophrenia: TDT and case‐control analyses

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Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder

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Prepulse inhibition of the startle reflex in rats: effects of compounds acting at various sites on the NMDA receptor complex.

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Kynurenic acid and 5,7-dichlorokynurenic acids improve social and object recognition in male rats

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Involvement of glutamatergic and dopaminergic systems in the reactivity of mice to spatial and non-spatial change.

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Pharmacological treatment of primary negative symptoms in schizophrenia: a systematic review

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12 December 2020

Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.

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12 December 2020

Phencyclidine does not disrupt latent inhibition in rats: implications for animal models of schizophrenia

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12 December 2020

D-serine added to antipsychotics for the treatment of schizophrenia

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12 December 2020

Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients

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12 December 2020

A genetic variant of the serine racemase gene is associated with schizophrenia

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12 December 2020

Dysfunctions in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R)

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12 December 2020

Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice

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12 December 2020

SSR181507, a putative atypical antipsychotic with dopamine D2 antagonist and 5-HT1A agonist activities: improvement of social interaction deficits induced by phencyclidine in rats

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12 December 2020

Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

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12 December 2020

Glutamate and schizophrenia: beyond the dopamine hypothesis

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12 December 2020

Latent inhibition is disrupted by nucleus accumbens shell lesion but is abnormally persistent following entire nucleus accumbens lesion: The neural site controlling the expression and disruption of the stimulus preexposure effect

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12 December 2020

Systemic administration of MK-801 produces an abnormally persistent latent inhibition which is reversed by clozapine but not haloperidol.

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12 December 2020

Identification of single nucleotide polymorphisms (SNPs) and other sequence changes and estimation of nucleotide diversity in coding and flanking regions of the NMDAR1 receptor gene in schizophrenic patients

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12 December 2020

Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered

1 reference

12 December 2020

Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia

1 reference

12 December 2020

The relation between latent inhibition and symptom-types in young schizophrenics

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12 December 2020

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice

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12 December 2020

Pathophysiologically based treatment interventions in schizophrenia

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12 December 2020

Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration.

1 reference

12 December 2020

10.1007/S00213-008-1196-6

Identifiers

DOI

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22 December 2017

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22 December 2017