(Q46240771)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23681101%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

The history of Toll-like receptors - redefining innate immunity (English)

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1 March 2020

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3

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1 March 2020

Luke A. J. O'Neill

series ordinal

1

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1 March 2020

2

Douglas Golenbock

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1 March 2020

publication date

17 May 2013

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Nature Reviews Immunology

1 March 2020

published in

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1 March 2020

volume

13

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1 March 2020

issue

6

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1 March 2020

page(s)

453-460

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Approaching the asymptote? Evolution and revolution in immunology

1 March 2020

cites work

1 reference

cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily

21 January 2018

1 reference

Drosophila Toll and IL-1 receptor

21 January 2018

1 reference

Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

21 January 2018

1 reference

Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel

21 January 2018

1 reference

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

21 January 2018

1 reference

Function and activation of NF-kappa B in the immune system

21 January 2018

1 reference

The product of the tobacco mosaic virus resistance gene N: similarity to toll and the interleukin-1 receptor

21 January 2018

1 reference

Dif, a dorsal-related gene that mediates an immune response in Drosophila.

21 January 2018

1 reference

Sequence and specificity of two antibacterial proteins involved in insect immunity

21 January 2018

1 reference

21 January 2018

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

1 reference

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila

21 January 2018

1 reference

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

A family of human receptors structurally related to Drosophila Toll

21 January 2018

1 reference

Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum

21 January 2018

1 reference

Recognition and plasma clearance of endotoxin by scavenger receptors

21 January 2018

1 reference

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

21 January 2018

1 reference

Structure and function of lipopolysaccharide binding protein

21 January 2018

1 reference

Soluble CD14 participates in the response of cells to lipopolysaccharide

21 January 2018

1 reference

Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin

21 January 2018

1 reference

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

21 January 2018

1 reference

Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.

21 January 2018

1 reference

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

1 reference

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling

21 January 2018

1 reference

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

21 January 2018

1 reference

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

21 January 2018

1 reference

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

1 reference

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

21 January 2018

1 reference

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

21 January 2018

1 reference

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells.

21 January 2018

1 reference

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

21 January 2018

1 reference

A toll-like receptor that prevents infection by uropathogenic bacteria

21 January 2018

1 reference

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

21 January 2018

1 reference

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

21 January 2018

1 reference

Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii

21 January 2018

1 reference

TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification

21 January 2018

1 reference

Sequence specific detection of bacterial 23S ribosomal RNA by TLR13.

21 January 2018

1 reference

Cutting edge: TLR13 is a receptor for bacterial RNA

21 January 2018

1 reference

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

21 January 2018

1 reference

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

21 January 2018

1 reference

Structures of the toll-like receptor family and its ligand complexes

21 January 2018

1 reference

Structural basis of TLR5-flagellin recognition and signaling

21 January 2018

1 reference

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

21 January 2018

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Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

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Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

1 reference

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

21 January 2018

1 reference

Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.

21 January 2018

1 reference

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

21 January 2018

1 reference

MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

21 January 2018

1 reference

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

1 reference

The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.

21 January 2018

1 reference

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

21 January 2018

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Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors

21 January 2018

1 reference

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

21 January 2018

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

21 January 2018

1 reference

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

21 January 2018

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MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.

21 January 2018

1 reference

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

1 reference

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

21 January 2018

1 reference

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling

21 January 2018

1 reference

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

21 January 2018

1 reference

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt

21 January 2018

1 reference

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

21 January 2018

1 reference

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

21 January 2018

1 reference

Taking toll: lipid A mimetics as adjuvants and immunomodulators

21 January 2018

1 reference

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

1 reference

Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guérin: involvement of toll-like receptors

21 January 2018

1 reference

Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2.

21 January 2018

1 reference

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

21 January 2018

1 reference

A phase II, double-blind, placebo-controlled, ascending-dose study of Eritoran (E5564), a lipid A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass.

21 January 2018

1 reference

Influence of severity of illness on the effects of eritoran tetrasodium (E5564) and on other therapies for severe sepsis

21 January 2018

1 reference

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

21 January 2018

1 reference

Genetic variation in Toll-like receptors and disease susceptibility

21 January 2018

1 reference

TLR3 deficiency in patients with herpes simplex encephalitis

21 January 2018

1 reference

Pyogenic bacterial infections in humans with MyD88 deficiency

21 January 2018

1 reference

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

21 January 2018

1 reference

Oncogenically active MYD88 mutations in human lymphoma

21 January 2018

1 reference

21 January 2018

For whom the bell tolls

1 reference

Control of B-cell responses by Toll-like receptors

21 January 2018

1 reference

Unresponsiveness of MyD88-deficient mice to endotoxin

21 January 2018

1 reference

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

31 March 2020

1 reference

Endotoxin-induced maturation of MyD88-deficient dendritic cells

31 March 2020

1 reference

Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs

31 March 2020

1 reference

Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury

31 March 2020

1 reference

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

31 March 2020

1 reference

12 December 2020

Interleukin-1 receptors.

1 reference

12 December 2020

Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.

1 reference

12 December 2020

Characterization of lipopolysaccharide from a heptoseless mutant of Escherichia coli by carbon 13 nuclear magnetic resonance

1 reference

12 December 2020

Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking.

1 reference

12 December 2020

Interleukin-1 and interleukin-1 antagonism

1 reference

12 December 2020

Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI3446

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23681101%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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