(Q44593854)

English

Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents

scientific article published in October 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 December 2017

Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Robert J Gillies

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

Natarajan Raghunand

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Brent P Mahoney

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

language of work or name

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publication date

1 October 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

Biochemical Pharmacology

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Europe PubMed Central

PubMed publication ID

4 December 2017

66

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1219-1229

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro

1 reference

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Enhancement of chemotherapy by manipulation of tumour pH.

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Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone

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Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer

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Carbonic anhydrase inhibitors: sulfonamides as antitumor agents?

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Increased intracellular drug accumulation and complete chemosensitization achieved in multidrug-resistant solid tumors by co-administering valspodar (PSC 833) with sterically stabilized liposomal doxorubicin.

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Pharmacological disposition of 1,4-dihydroxy-5-8-bis[[2 [(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride in the dog.

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7 January 2021

Pharmacokinetics and metabolism of mitoxantrone. A review

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Pharmacokinetics of Doxorubicin in Man with Induced Acid or Alkaline Urine

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Pharmacokinetics of doxorubicin and its metabolite doxorubicinol in rabbits with induced acid and alkaline urine

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Doxorubicin pharmacokinetics after intravenous and intraperitoneal administration in the nude mouse

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Mitoxantrone metabolism in the isolated perfused rat liver

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Pharmacology of mitoxantrone in cancer patients

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The effects of impaired liver function on the elimination of antineoplastic agents

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pH and drug resistance in tumors.

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The relevance of tumour pH to the treatment of malignant disease

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Extracellular pH distribution in human tumours

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7 January 2021

Studies of human tumors by MRS: a review

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7 January 2021

Are cancer cells acidic?

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Analysis and management of renal failure in fourth MRC myelomatosis trial. MRC working party on leukaemia in adults

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7 January 2021

Modification of human tumour and normal tissue pH during hyperthermic and normothermic antiblastic regional isolation perfusion for malignant melanoma: a pilot study

1 reference

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7 January 2021

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Identifiers

10.1016/S0006-2952(03)00468-4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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