(Q44386905)

2 December 2017

title

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease (English)

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2 December 2017

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15

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2 December 2017

Rapee Boonplueang

6

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Julie K Andersen

object named as

Julie K Andersen

16

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M. Flint Beal

10

object named as

M Flint Beal

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2 December 2017

Deepinder Kaur

1

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2 December 2017

Ferda Yantiri

2

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2 December 2017

Subramanian Rajagopalan

3

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2 December 2017

Jyothi Kumar

4

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2 December 2017

Jun Qin Mo

5

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2 December 2017

Veena Viswanath

7

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2 December 2017

Russell Jacobs

8

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2 December 2017

Lichuan Yang

9

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2 December 2017

Dino DiMonte

11

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2 December 2017

Irene Volitaskis

12

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2 December 2017

Lisa Ellerby

13

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2 December 2017

Robert A Cherny

14

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2 December 2017

language of work or name

English

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publication date

1 March 2003

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2 December 2017

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2 December 2017

volume

37

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2 December 2017

issue

6

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2 December 2017

page(s)

899-909

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Oxygen free radicals and Parkinson's disease

2 December 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Release of iron from ferritin by metabolites of benzene and superoxide radical generating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

5' flanking sequences of the rat tyrosine hydroxylase gene target accurate tissue-specific, developmental, and transsynaptic expression in transgenic mice

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

MR evaluation of age-related increase of brain iron in young adult and older normal males

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Neurotoxicity of halogenated hydroxyquinolines: clinical analysis of cases reported outside Japan

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Experimental models of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Ferritin, transferrin, and iron in selected regions of the adult and aged rat brain

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Brain iron pathways and their relevance to Parkinson's disease.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Animal models of Parkinson's disease.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Metals and neuroscience.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Sequestration of iron by Lewy bodies in Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Free Radicals and MPTP-Induced Selective Destruction of Substantia Nigra Cornpacta Neurons

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Oxidative stress and Alzheimer disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Isoforms of ferritin have a specific cellular distribution in the brain

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron and iron management proteins in neurobiology

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Increased nigral iron content in postmortem parkinsonian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

In vitro studies of ferritin iron release and neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The potential role of iron chelators in the treatment of Parkinson's disease and related neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Altered brain metabolism of iron as a cause of neurodegenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

1 reference

7 January 2021

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron and oxygen radicals in brain

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The ferritins: molecular properties, iron storage function and cellular regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The regional distribution and cellular localization of iron in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

MPTP Produces Differential Oxidative Stress and Antioxidative Responses in the Nigrostriatal and Mesolimbic Dopaminergic Pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The role of iron in neurodegeneration: prospects for pharmacotherapy of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Brain iron and ferritin in Parkinson's and Alzheimer's diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

New insights into the cause of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Excessive iron accumulation in the brain: A possible potential risk of neurodegeneration in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Complex I, iron, and ferritin in Parkinson's disease substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

'...and C is for Clioquinol' - the AbetaCs of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Relation between subacute myelo-optic neuropathy (S.M.O.N.) and clioquinol: nationwide survey

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Ferritin and the response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Parkinson's disease: a disorder due to nigral glutathione deficiency?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The toxic effects of desferrioxamine

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Role of H and L subunits in mouse ferritin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Subacute myelo-optico-neuropathy: clioquinol intoxication in humans and animals

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Neurological syndrome associated with clioquinol

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

New stereological methods for counting neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Changes in uptake of vitamin B(12) and trace metals in brains of mice treated with clioquinol

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

XANES spectroscopy of a single neuron from a patient with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The same chemicals induce different neurotoxicity when administered in high doses for short term or low doses for long term to rats and dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

The possible role of iron in the etiopathology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900126-0

7 January 2021

10.1016/S0896-6273(03)00126-0

Identifiers

DOI

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2 December 2017

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