(Q44226596)

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In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12447687%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12447687%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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1

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15 December 2019

Riccardo Vigneri

5

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15 December 2019

Antonino Belfiore

6

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15 December 2019

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Rossana Mineo

2

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15 December 2019

Giuseppe Pandini

3

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15 December 2019

Antonella Murabito

4

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15 December 2019

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1 November 2002

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Europe PubMed Central

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15 December 2019

1 reference

Europe PubMed Central

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15 December 2019

21

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15 December 2019

54

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15 December 2019

8240-8250

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15 December 2019

Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts

1 reference

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Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor

1 reference

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Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.

1 reference

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Insulin-like growth factor expression in breast cancer epithelium and stroma

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The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

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Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

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A monoclonal anti-peptide antibody reacting with the insulin receptor β-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptors

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Insulin is a potent survival factor in mesangial cells: role of the PI3-kinase/Akt pathway

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Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I

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Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

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Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor

1 reference

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7 January 2021

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

1 reference

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7 January 2021

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Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

1 reference

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Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action

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Orthopaedic and trauma surgery. Best method of anterior cruciate ligament reconstruction is debated

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Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

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Tumour-induced hypoglycaemia due to 'big' IGF-II

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A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer

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