(Q43990736)

28 November 2017

title

Structural refinement of inhibitors of urea-based soluble epoxide hydrolases (English)

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28 November 2017

Christophe Morisseau

1

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28 November 2017

Marvin H Goodrow

2

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28 November 2017

John W Newman

3

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28 November 2017

Craig E Wheelock

4

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28 November 2017

Deanna L Dowdy

5

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28 November 2017

Bruce D Hammock

6

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28 November 2017

language of work or name

English

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publication date

1 May 2002

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28 November 2017

published in

Biochemical Pharmacology

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28 November 2017

volume

63

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28 November 2017

issue

9

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28 November 2017

page(s)

1599-1608

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Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

28 November 2017

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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

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A new class of lipid mediators: cytochrome P450 arachidonate metabolites

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Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation

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Cytochrome P450 2C is an EDHF synthase in coronary arteries

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Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

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Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation

7 January 2021

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Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

7 January 2021

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New role for epoxyeicosatrienoic acids as anti-inflammatory mediators

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Endothelin-1 potentiates leukotoxin-induced edematous lung injury

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Lipid oxidation products in ischemic porcine heart tissue

7 January 2021

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Cardiovascular effects of leukotoxin (9, 10-epoxy-12-octadecenoate) and free fatty acids in dogs

7 January 2021

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Potent urea and carbamate inhibitors of soluble epoxide hydrolases

7 January 2021

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Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase

7 January 2021

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Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation

7 January 2021

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Evaluation of fish models of soluble epoxide hydrolase inhibition

7 January 2021

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cDNA cloning and expression of a soluble epoxide hydrolase from human liver

7 January 2021

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Affinity purification of cytosolic epoxide hydrolase using derivatized epoxy-activated Sepharose gels

7 January 2021

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Improved radiolabeled substrates for soluble epoxide hydrolase

7 January 2021

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Spectrophotometric substrates for cytosolic epoxide hydrolase

7 January 2021

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The graphical determination of Km and Ki

7 January 2021

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3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues

7 January 2021

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Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition

7 January 2021

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The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase

7 January 2021

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Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase

7 January 2021

1 reference

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10.1016/S0006-2952(02)00952-8

7 January 2021

Identifiers

DOI

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28 November 2017

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