(Q43627216)

25 November 2017

title

Kinetic dependence to HIV-1 entry inhibition (English)

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25 November 2017

H Kirby Steger

1

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25 November 2017

Michael J Root

series ordinal

2

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25 November 2017

language of work or name

English

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publication date

27 June 2006

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Journal of Biological Chemistry

25 November 2017

published in

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25 November 2017

volume

281

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25 November 2017

issue

35

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25 November 2017

page(s)

25813-25821

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Mechanisms of viral membrane fusion and its inhibition

25 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601457200

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Core structure of gp41 from the HIV envelope glycoprotein

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Atomic structure of the ectodomain from HIV-1 gp41

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Atomic structure of a thermostable subdomain of HIV-1 gp41

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Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

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Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

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Capture of an early fusion-active conformation of HIV-1 gp41

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Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope

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Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

21 January 2018

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Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

21 January 2018

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The cytoplasmic tail slows the folding of human immunodeficiency virus type 1 Env from a late prebundle configuration into the six-helix bundle

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Dilation of the Human Immunodeficiency Virus–1 Envelope Glycoprotein Fusion Pore Revealed by the Inhibitory Action of a Synthetic Peptide from gp41

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Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America

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Design and properties of N(CCG)-gp41, a chimeric gp41 molecule with nanomolar HIV fusion inhibitory activity

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Protein design of an HIV-1 entry inhibitor

21 January 2018

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Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection

21 January 2018

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Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.

21 January 2018

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Targeting therapeutics to an exposed and conserved binding element of the HIV-1 fusion protein

21 January 2018

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The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions.

21 January 2018

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Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation.

21 January 2018

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Genetic evidence that interhelical packing interactions in the gp41 core are critical for transition of the human immunodeficiency virus type 1 envelope glycoprotein to the fusion-active state

21 January 2018

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Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

21 January 2018

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Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site

21 January 2018

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Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

21 January 2018

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Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

21 January 2018

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

21 January 2018

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

21 January 2018

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HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation

21 January 2018

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Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion

21 January 2018

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Short constrained peptides that inhibit HIV-1 entry

21 January 2018

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Identification of a major co-receptor for primary isolates of HIV-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M601457200

1 reference

25 November 2017

1 reference