(Q42797512)

English

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

scientific article published on 2 September 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

author name string

Victoria Rotter

1

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Ivan Nagaev

2

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Ulf Smith

3

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

language of work or name

0 references

publication date

2 September 2003

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

45777-45784

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-alpha or its receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

TNF-alpha and insulin resistance: summary and future prospects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Distinct long-term regulation of glycerol and non-esterified fatty acid release by insulin and TNF-alpha in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Interleukin-6 enhances glucose transport in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Comparison of the effects of insulin, PDGF, interleukin-6, and interferon-gamma on glucose transport in 3T3-L1 cells: lack of cross-talk between tyrosine kinase receptors and JAK/STAT pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Radiometric assays for glycerol, glucose, and glycogen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Opposite regulation of interleukin-8 and tumor necrosis factor-alpha by weight loss

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Hormone Replacement Therapy and Interrelation between Serum Interleukin-6 and Body Mass Index in Postmenopausal Women: A Population-Based Study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301977200

21 January 2018

Identifiers

10.1074/JBC.M301977200

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

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