(Q42486098)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Andy Y Shih

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Ping Li

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Timothy H Murphy

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

1 November 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

10321-10335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

8 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725780/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Evaluation of certain food additives and contaminants. Forty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives

1 reference

12 December 2020

The changing landscape of ischaemic brain injury mechanisms.

1 reference

12 December 2020

Pathobiology of ischaemic stroke: an integrated view

1 reference

12 December 2020

Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism

1 reference

12 December 2020

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

1 reference

12 December 2020

Ischemic cell death in brain neurons

1 reference

12 December 2020

Evidence for a protective role of metallothionein-1 in focal cerebral ischemia

1 reference

12 December 2020

Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes

1 reference

12 December 2020

Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

1 reference

12 December 2020

Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid

1 reference

12 December 2020

Dynamics of regional brain metabolism and gene expression after middle cerebral artery occlusion in mice

1 reference

12 December 2020

Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.

1 reference

12 December 2020

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

1 reference

12 December 2020

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

1 reference

12 December 2020

Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion

1 reference

12 December 2020

Evolution of brain infarction after transient focal cerebral ischemia in mice

1 reference

12 December 2020

Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons

1 reference

12 December 2020

Differences in vulnerability to permanent focal cerebral ischemia among 3 common mouse strains

1 reference

12 December 2020

Free radical pathways in CNS injury

1 reference

12 December 2020

Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

1 reference

12 December 2020

Neurochemical changes and laser Doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia

1 reference

12 December 2020

The effects of LY393613, nimodipine and verapamil, in focal cerebral ischaemia

1 reference

12 December 2020

Reactive oxygen radicals in signaling and damage in the ischemic brain

1 reference

12 December 2020

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

1 reference

12 December 2020

Chemoprotection against cancer by induction of phase 2 enzymes

1 reference

12 December 2020

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

12 December 2020

Preferential expression of antioxidant response element mediated gene expression in astrocytes

1 reference

12 December 2020

The antioxidant enzyme quinone reductase is up-regulated in vivo following cerebral ischemia

1 reference

12 December 2020

The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes

1 reference

12 December 2020

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione

1 reference

12 December 2020

Toxicological evaluation of some food additives, including food colours, thickening agents and others. Joint FAO/WHO Expert Committee on Food Additives. Geneva, 14-23 April 1975

1 reference

12 December 2020

Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

1 reference

12 December 2020

A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats.

1 reference

12 December 2020

Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells

1 reference

12 December 2020

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

1 reference

12 December 2020

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

1 reference

12 December 2020

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

12 December 2020

Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat.

1 reference

12 December 2020

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

1 reference

12 December 2020

Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes

1 reference

12 December 2020

Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: the role of nitric oxide synthase in rat glutathione S-transferase A2 induction

1 reference

12 December 2020

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

1 reference

12 December 2020

Examination of sensorimotor performance following middle cerebral artery occlusion in rats

1 reference

12 December 2020

NTP Toxicology and Carcinogenesis Studies of t-Butylhydroquinone (CAS No. 1948-33-0) in F344/N Rats and B6C3F(1) Mice (Feed Studies).

1 reference

12 December 2020

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

1 reference

12 December 2020

Mechanisms, challenges and opportunities in stroke

1 reference

12 December 2020

1 reference

12 December 2020

Effect of resuscitative mild hypothermia on glutamate and dopamine release, apoptosis and ischaemic brain damage in the endothelin-1 rat model for focal cerebral ischaemia

1 reference

12 December 2020

Venous smooth muscle contains vasoconstrictor ETB-like receptors

1 reference

12 December 2020

The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo

1 reference

12 December 2020

The glutathione conjugates of tert-butyl hydroquinone as potent redox cycling agents and possible reactive agents underlying the toxicity of butylated hydroxyanisole

1 reference

12 December 2020

ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo

1 reference

12 December 2020

Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)

1 reference

12 December 2020

Focal lesions in the rat central nervous system induced by endothelin-1.

1 reference

12 December 2020

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

1 reference

12 December 2020

Stress protein activation by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in human mesangial cells

1 reference

12 December 2020

PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress

1 reference

12 December 2020

The effects of intracortical endothelin-1 injections on skilled forelimb use: implications for modelling recovery of function after stroke

1 reference

12 December 2020

Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system

1 reference

12 December 2020

Sodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence.

1 reference

12 December 2020

Response of the brain to oligemia: gene expression, c-Fos, and Nrf2 localization

1 reference

12 December 2020

Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat.

1 reference

12 December 2020

Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

1 reference

12 December 2020

On-line monitoring of striatum glucose and lactate in the endothelin-1 rat model of transient focal cerebral ischemia using microdialysis and flow-injection analysis with biosensors

1 reference

12 December 2020

Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

1 reference

12 December 2020

Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats

1 reference

12 December 2020

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

1 reference

12 December 2020

Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia.

1 reference

12 December 2020

Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Enhanced NAD(P)H:Quinone Reductase Activity Prevents Glutamate Toxicity Produced by Oxidative Stress

1 reference

12 December 2020

Rat middle cerebral artery occlusion using an intraluminal thread technique

1 reference

12 December 2020

Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

1 reference

12 December 2020

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1 reference

12 December 2020

Reversible middle cerebral artery occlusion without craniectomy in rats

1 reference

12 December 2020

Mechanisms of induction of enzymes that protect against chemical carcinogenesis

1 reference

12 December 2020

Autonomic and myocardial changes in middle cerebral artery occlusion: stroke models in the rat

1 reference

12 December 2020

Role of cytochrome P1-450 in the induction of NAD(P)H:quinone reductase in a murine hepatoma cell line and its mutants.

1 reference

12 December 2020

Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression

1 reference

12 December 2020

Focal ischemia of the rat brain: autoradiographic determination of cerebral glucose utilization, glucose content, and blood flow

1 reference

12 December 2020

Physiological concentrations of lactate dehydrogenases and substrate inhibition

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Focal cerebral ischemia in the rat: topography of hemodynamic and histopathological changes

1 reference

12 December 2020

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

12 December 2020

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

1 reference

12 December 2020

The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

1 reference

12 December 2020

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

1 reference

12 December 2020

Endothelin-1 induced middle cerebral artery occlusion: pathological consequences and neuroprotective effects of MK801.

1 reference

12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

12 December 2020

Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat

1 reference

12 December 2020

Chemoprotection against cancer by phase 2 enzyme induction

1 reference

12 December 2020

Evolving stroke and the ischemic penumbra

1 reference

12 December 2020

Periinfarct depolarizations.

1 reference

12 December 2020

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

1 reference

12 December 2020

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

1 reference

12 December 2020

Construction of adenovirus vectors through Cre-lox recombination

1 reference

12 December 2020

Apoptosis in the striatum of rats following intraperitoneal injection of 3-nitropropionic acid

1 reference

12 December 2020

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

1 reference

12 December 2020

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1 reference

12 December 2020

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

1 reference

12 December 2020

1 reference

12 December 2020

Endothelin-B Receptors in Cerebral Resistance Arterioles and their Functional Significance after Focal Cerebral Ischemia in Cats

1 reference

12 December 2020

Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat.

1 reference

12 December 2020

Histochemical Detection of Quinone Reductase Activity In Situ Using LY 83583 Reduction and Oxidation

1 reference

12 December 2020

Cerebral Ischemia after Bilateral Carotid Artery Occlusion and Intraluminal Suture Occlusion in Mice: Evaluation of the Patency of the Posterior Communicating Artery

1 reference

12 December 2020

Differences in the cerebrovascular anatomy of C57black/6 and SV129 mice

1 reference

12 December 2020

Activation of endogenous antioxidant defenses in neuronal cells prevents free radical-mediated damage.

1 reference

12 December 2020

Evaluation of morphological changes after treatment with coenzyme Q10 (CoQ10) in endothelin-1 induced experimental ischemia in the rat.

1 reference

12 December 2020

Focal cerebral ischemia in the mouse: description of a model and effects of permanent and temporary occlusion

1 reference

12 December 2020

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

12 December 2020

Coordinate regulation of NAD(P)H:quinone oxidoreductase and glutathione-S-transferases in primary cultures of rat neurons and glia: role of the antioxidant/electrophile responsive element

1 reference

12 December 2020

Oxidative stress in brain ischemia.

1 reference

12 December 2020

10.1523/JNEUROSCI.4014-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16267240%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

16267240

1 reference