(Q424716)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04180

Alpha/Beta hydrolase fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04180

image

LCAT protein.png
1,920 × 975; 735 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

1 reference

8 April 2019

O-acyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

1 reference

8 April 2019

apolipoprotein A-I binding

1 reference

8 April 2019

Interaction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol vesicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

protein binding

3 references

8 April 2019

Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Interaction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol vesicles

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

acyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

1 reference

8 April 2019

phosphatidylcholine-sterol O-acyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

7 references

8 April 2019

TAS

8 April 2019

Role of the interfacial binding domain in the oxidative susceptibility of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

The high-resolution crystal structure of human LCAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

high-density lipoprotein particle

cell component

1 reference

8 April 2019

Distribution and localization of lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity in A-I-containing lipoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

extracellular exosome

extracellular space

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Cloning and expression of human lecithin-cholesterol acyltransferase cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

extracellular exosome

HDA

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

steroid metabolic process

HDA

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

1 reference

8 April 2019

regulation of high-density lipoprotein particle assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

cholesterol transport

1 reference

8 April 2019

Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

cholesterol metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

The high-resolution crystal structure of human LCAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

cholesterol esterification

3 references

8 April 2019

The high-resolution crystal structure of human LCAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Cloning and expression of human lecithin-cholesterol acyltransferase cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

very-low-density lipoprotein particle remodeling

1 reference

8 April 2019

Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

phospholipid metabolic process

1 reference

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

lipoprotein biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

cholesterol homeostasis

1 reference

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

phosphatidylcholine biosynthetic process

1 reference

8 April 2019

Role of the interfacial binding domain in the oxidative susceptibility of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

phosphatidylcholine metabolic process

1 reference

8 April 2019

The high-resolution crystal structure of human LCAT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

reverse cholesterol transport

1 reference

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

high-density lipoprotein particle remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

5 references

8 April 2019

TAS

8 April 2019

Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

Remodeling of HDL remnants generated by scavenger receptor class B type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

ApoA-I structure on discs and spheres. Variable helix registry and conformational states

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

8 April 2019

A protein cofactor of lecithin:cholesterol acyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04180

http://purl.uniprot.org/uniprot/P04180

exact match

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers.org

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016