(Q42447064)

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Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains

scientific article published on 3 September 2003

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Europe PubMed Central

PubMed publication ID

31 October 2017

Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Michelle A Digman

3

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Michelle A Digman

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Europe PubMed Central

PubMed publication ID

31 October 2017

author name string

Bharath Ananthanarayanan

1

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Europe PubMed Central

PubMed publication ID

31 October 2017

Robert V Stahelin

2

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Europe PubMed Central

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31 October 2017

Wonhwa Cho

4

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Europe PubMed Central

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31 October 2017

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publication date

3 September 2003

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Europe PubMed Central

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31 October 2017

number of pages

9

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Journal of Biological Chemistry

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Europe PubMed Central

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31 October 2017

278

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Europe PubMed Central

PubMed publication ID

31 October 2017

47

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Europe PubMed Central

PubMed publication ID

31 October 2017

46886-46894

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Europe PubMed Central

PubMed publication ID

31 October 2017

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

1 reference

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Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

1 reference

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Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Membrane targeting by C1 and C2 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Novel "nonkinase" phorbol ester receptors: the C1 domain connection

1 reference

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21 January 2018

Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters.

1 reference

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21 January 2018

Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold

1 reference

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21 January 2018

The C2 domain calcium-binding motif: structural and functional diversity

1 reference

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21 January 2018

C2-domains, structure and function of a universal Ca2+-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Protein kinase C. Seeing two domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Non-equivalent roles for the first and second zinc fingers of protein kinase Cdelta. Effect of their mutation on phorbol ester-induced translocation in NIH 3T3 cells

1 reference

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21 January 2018

Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.

1 reference

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21 January 2018

Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.

1 reference

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21 January 2018

Differential roles of ionic, aliphatic, and aromatic residues in membrane-protein interactions: a surface plasmon resonance study on phospholipases A2.

1 reference

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21 January 2018

A structure-function study of the C2 domain of cytosolic phospholipase A2. Identification of essential calcium ligands and hydrophobic membrane binding residues.

1 reference

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21 January 2018

Membrane binding assays for peripheral proteins.

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21 January 2018

The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.

1 reference

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21 January 2018

NMR Structure of a Protein Kinase C-γ Phorbol-Binding Domain and Study of Protein−Lipid Micelle Interactions

1 reference

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21 January 2018

Surface plasmon resonance spectroscopy: an emerging tool for the study of peptide-membrane interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Surface plasmon resonance spectroscopy in the study of membrane-mediated cell signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Regulation of PKC alpha activity by C1-C2 domain interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state

1 reference

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21 January 2018

Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents

1 reference

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21 January 2018

A comparative study of the phase transitions of phospholipid bilayers and monolayers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Lateral pressure in membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307853200

21 January 2018

Protein kinase C gamma (PKC gamma): function of neuron specific isotype

1 reference

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21 January 2018

Studies on the primary sequence requirements for PKC-α, -β1 and -γ peptide substrates

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M307853200

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

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