(Q42121453)

English

Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes

scientific article published on September 1993

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

phosphatidylcholine

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

N J Reynolds

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

H S Talwar

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

J J Baldassare

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

P A Henderson

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

J T Elder

5

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

J J Voorhees

6

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

G J Fisher

7

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

0 references

publication date

1 September 1993

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

294 ( Pt 2)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

535-544

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Epidermal growth factor-like transforming growth factor. I. Isolation, chemical characterization, and potentiation by other transforming factors from feline sarcoma virus-transformed rat cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Ca2+-mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Detection of transforming growth factor alpha in normal, malignant, and hyperproliferative human keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Quantitative measurement of sn-1,2-diacylglycerols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Studies and perspectives of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Cell-mediated co-action of transforming growth factors: incubation of type beta with normal rat kidney cells produces a soluble activity that prolongs the ruffling response to type alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Induction of transforming growth factor-alpha expression in human keratinocytes by phorbol esters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Phorbol ester stimulates the hydrolysis of phosphatidylethanolamine in leukemic HL-60, NIH 3T3, and baby hamster kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Global modulation of the epidermal growth factor receptor is triggered by occupancy of only a few receptors. Evidence for a binary regulatory system in normal human fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Molecular species analysis of 1,2-diglycerides stimulated by alpha-thrombin in cultured fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Phosphoinositide metabolism and the control of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Action of phorbol esters, bryostatins, and retinoic acid on cholesterol sulfate synthesis: relation to the multistep process of differentiation in human epidermal keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Bradykinin transiently activates protein kinase C in Swiss 3T3 cells. Distinction from activation by bombesin and vasopressin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

TGF-alpha and TGF-beta expression during sodium-N-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of TGF-beta mRNA in suprabasal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Bradykinin induces phosphoinositide turnover, 1,2-diglyceride formation, and growth in cultured adult human keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

The temporal relationship between phospholipase activation, diradylglycerol formation and superoxide production in the human neutrophil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Neuropeptide Y stimulation of myosin light chain phosphorylation in cultured aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Effects of substitution of threonine 654 of the epidermal growth factor receptor on epidermal growth factor-mediated activation of phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Signaling through phosphatidylcholine breakdown.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Epidermal growth factor-induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Growth factor-independent proliferation of normal human neonatal keratinocytes: production of autocrine- and paracrine-acting mitogenic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Phospholipase D in cell signalling and its relationship to phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Role of phospholipase in generating lipid second messengers in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Existence of cytosolic phospholipase D. Identification and comparison with membrane-bound enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Modulation of phospholipase A2 activity by epidermal growth factor (EGF) in CHO cells transfected with human EGF receptor. Role of receptor cytoplasmic subdomain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Epidermal growth factor and transforming growth factor-alpha: differential intracellular routing and processing of ligand-receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Platelet activation by simultaneous actions of diacylglycerol and unsaturated fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Patterns of acetylcholine phosphocholine, and choline phosphoglycerides labeling from (methyl-14C)choline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

29 May 2018

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

17 August 2018

Epidermal growth factor activates phosphoinositide turnover and protein kinase C in BALB/MK keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

17 August 2018

The effects of epidermal growth factor and the state of confluence on enzymatic activities of cultured rat liver epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134488

1 December 2018

Phospholipid metabolism in bradykinin-stimulated human fibroblasts. I. Biphasic formation of diacylglycerol from phosphatidylinositol and phosphatidylcholine, controlled by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine in psoriasis treatment. Inhibition of keratinocyte cell-cycle progression in G1 independent of effects on transforming growth factor alpha/epidermal growth factor receptor pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of TGF-alpha expression in human keratinocytes: PKC-dependent and -independent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-induced hydrolysis of phosphoinositides and formation of 1,2-diacylglycerol in adult human keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic peptide-stimulated human neutrophils. Involvement of phosphatidate phosphohydrolase in signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 125I-epidermal growth factor binding to cultured keratinocytes by antiproliferative molecules gamma interferon, cyclosporin A, and transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of transforming growth factor alpha in psoriatic epidermis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin A potentiates the mitogenic effect of epidermal growth factor in cultures of normal adult human skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

125I-EGF binding to responsive and nonresponsive cells in culture: loss of cell-associated radioactivity relates to growth induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production and auto-induction of transforming growth factor-α in human keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor (EGF) produces inositol phosphates and increases cytoplasmic free calcium in cultured porcine thyroid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells by calcium and protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of diacylglycerol by a phospholipase D-phosphatidate phosphatase pathway specific for phosphatidylcholine in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of protein kinase C activation and sn-1,2-diacylglycerol formation. Comparison of phosphatidylinositol- and phosphatidylcholine-derived diglycerides in alpha-thrombin-stimulated fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7690546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2940535

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

ResearchGate publication ID

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