(Q42072108)

16 October 2017

Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling (English)

1 reference

Intraflagellar transport 172

16 October 2017

0 references

1 reference

Intraflagellar transport 57 homolog (Chlamydomonas)

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Shannon C Lunt

series ordinal

1

1 reference

16 October 2017

Tony Haynes

series ordinal

2

1 reference

16 October 2017

Brian D Perkins

series ordinal

3

1 reference

16 October 2017

language of work or name

1 reference

1 July 2009

1 reference

16 October 2017

Developmental Dynamics

1 reference

16 October 2017

238

1 reference

16 October 2017

7

1 reference

16 October 2017

1744-1759

1 reference

The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Ciliary proteins link basal body polarization to planar cell polarity regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The graded response to Sonic Hedgehog depends on cilia architecture

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Hippi is essential for node cilia assembly and Sonic hedgehog signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Overview of structure and function of mammalian cilia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Proteomics of early zebrafish embryos

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Vertebrate Smoothened functions at the primary cilium

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Gli function is essential for motor neuron induction in zebrafish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

5 June 2018

Intraflagellar Transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

5 June 2018

Intraflagellar transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Use of real-time quantitative PCR to validate the results of cDNA array and differential display PCR technologies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Genetic analysis of photoreceptor cell development in the zebrafish retina

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Hedgehog signaling in animal development: paradigms and principles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Specification and morphogenesis of the zebrafish larval head skeleton

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A large-scale insertional mutagenesis screen in zebrafish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A Critical Period of Ear Development Controlled by Distinct Populations of Ciliated Cells in the Zebrafish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Mutations affecting development of the midline and general body shape during zebrafish embryogenesis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Stages of embryonic development of the zebrafish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A motility in the eukaryotic flagellum unrelated to flagellar beating

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Axonogenesis in the brain of zebrafish embryos

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Mitotic domains in the early embryo of the zebrafish

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

dazed gene is necessary for late cell type development and retinal cell maintenance in the zebrafish retina

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Zebrafish smoothened functions in ventral neural tube specification and axon tract formation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

The shaping of pharyngeal cartilages during early development of the zebrafish.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Midline signalling is required for Pax gene regulation and patterning of the eyes.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice

17 August 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771627

Cell cycles and clonal strings during formation of the zebrafish central nervous system

1 December 2018

1 reference

12 December 2020

Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes

1 reference

12 December 2020

Identification of separate slow and fast muscle precursor cells in vivo, prior to somite formation

1 reference

12 December 2020

Function for Hedgehog genes in zebrafish retinal development

1 reference

12 December 2020

Mutations affecting development of the zebrafish retina

1 reference

12 December 2020

Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Identification of zebrafish insertional mutants with defects in visual system development and function

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Hedgehog signalling in the mouse requires intraflagellar transport proteins

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Pax genes in eye development and evolution

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Intraflagellar transport is required for the vectorial movement of TRPV channels in the ciliary membrane

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Loss of the Tg737 protein results in skeletal patterning defects

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Modulation of zebrafish pitx3 expression in the primordia of the pituitary, lens, olfactory epithelium and cranial ganglia by hedgehog and nodal signaling

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21999

7 January 2021

Identifiers

DOI

10.1002/DVDY.21999

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

19517571

1 reference