(Q41743616)

8 October 2017

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title

A summary of mechanistic hypotheses of gabapentin pharmacology (English)

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8 October 2017

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C P Taylor

1

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8 October 2017

N S Gee

2

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8 October 2017

T Z Su

3

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8 October 2017

J D Kocsis

4

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8 October 2017

D F Welty

5

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8 October 2017

J P Brown

6

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8 October 2017

D J Dooley

7

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8 October 2017

P Boden

8

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8 October 2017

L Singh

9

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8 October 2017

publication date

1 February 1998

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8 October 2017

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8 October 2017

volume

29

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8 October 2017

issue

3

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8 October 2017

page(s)

233-249

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Gabapentin monotherapy: II. A 26-week, double-blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory complex partial or secondarily generalized seizures

8 October 2017

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The anticonvulsant gabapentin decreases firing rates of substantia nigra pars reticulata neurons

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7 January 2021

GABAB receptor pharmacology

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Use of site-directed antibodies to probe the topography of the alpha 2 subunit of voltage-gated Ca2+ channels

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Gabapentin monotherapy: I. An 8-day, double-blind, dose controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures

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7 January 2021

Structure and function of voltage-gated ion channels

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The G.L. Brown Prize Lecture. Voltage-dependent calcium channels and their modulation by neurotransmitters and G proteins

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7 January 2021

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

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Hippocampal GABA transporter function in temporal-lobe epilepsy

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Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel

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7 January 2021

The structural and functional heterogeneity of glutamic acid decarboxylase: A review

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Two genes encode distinct glutamate decarboxylases

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Gabapentin (neurontin) and S‐(+)‐3‐isobutylgaba represent a novel class of selective antihyperalgesic agents

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7 January 2021

Neurobiology. Taking apart NMDA receptors

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The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

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7 January 2021

Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA

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7 January 2021

Experimental studies of the influence of vigabatrin on the GABA system

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7 January 2021

Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction.

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7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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7 January 2021

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

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7 January 2021

Subunit composition of the purified dihydropyridine binding protein from skeletal muscle

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7 January 2021

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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7 January 2021

Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies

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7 January 2021

Molecular basis for Ca2+ channel diversity

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7 January 2021

Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro

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7 January 2021

The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis

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7 January 2021

The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain

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7 January 2021

Effect of subarachnoid gabapentin on tactile-evoked allodynia in a surgically induced neuropathic pain model in the rat

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7 January 2021

gamma-Aminobutyric acid transport in reconstituted preparations from rat brain: coupled sodium and chloride fluxes

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7 January 2021

Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve

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7 January 2021

Neurochemical actions of gabapentin in mouse brain

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7 January 2021

Studies on uptake of γ-aminobutyric acid by mouse brain particles; toward the development of a model

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7 January 2021

Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain

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7 January 2021

GABAA receptor channels

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7 January 2021

New antiepileptic drugs: a systematic review of their efficacy and tolerability

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7 January 2021

Formalin induces biphasic activity in C-fibers in the rat

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7 January 2021

Erythromelalgia pain managed with gabapentin

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7 January 2021

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7 January 2021

Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. The US Gabapentin Study Group No. 5

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7 January 2021

Reflex sympathetic dystrophy treated with gabapentin

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7 January 2021

Gabapentin in the management of reflex sympathetic dystrophy

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7 January 2021

Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group

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7 January 2021

Primary structure and functional expression from complementary DNA of a brain calcium channel

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7 January 2021

Transient presence of GABA in astrocytes of the developing optic nerve.

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7 January 2021

The antidepressant drug phenelzine produces antianxiety effects in the plus-maze and increases in rat brain GABA.

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7 January 2021

The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy

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7 January 2021

Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture

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7 January 2021

Glutamate dysfunction and selective motor neuron degeneration in amyotrophic lateral sclerosis: a hypothesis

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7 January 2021

Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

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7 January 2021

Reduction of 3,4-diaminopyridine-induced biogenic amine synthesis and release in rat brain by gabapentin

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7 January 2021

Gabapentin augments whole blood serotonin in healthy young men

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7 January 2021

Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?

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7 January 2021

Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons

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7 January 2021

Gabapentin adjunctive therapy in neuropathic pain states

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7 January 2021

Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity

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7 January 2021

Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy

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7 January 2021

Ca2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: contribution of changes in channel gating and alpha 1 protein level

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7 January 2021

The roles of the subunits in the function of the calcium channel

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7 January 2021

The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist

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7 January 2021

The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine

1 reference

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7 January 2021

Gabapentin inhibits calcium currents in isolated rat brain neurons

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7 January 2021

A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma

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7 January 2021

Transport of gabapentin, a gamma-amino acid drug, by system l alpha-amino acid transporters: a comparative study in astrocytes, synaptosomes, and CHO cells

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7 January 2021

Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies

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7 January 2021

A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor

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7 January 2021

Quantitative autoradiographic characterization of the binding of [3H]tiagabine (NNC 05-328) to the GABA uptake carrier

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7 January 2021

Effect of nipecotic acid, a gamma-aminobutyric acid transport inhibitor, on the turnover and release of gamma-aminobutyric acid in rat cortical slices

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7 January 2021

Glutamate decarboxylase activity in the substantia nigra and the hippocampus of rats microinjected with inhibitors of the enzyme

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7 January 2021

3-Alkyl GABA and 3-alkylglutamic acid analogues: two new classes of anticonvulsant agents

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7 January 2021

Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin

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7 January 2021

[3H]gabapentin may label a system-L-like neutral amino acid carrier in brain

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7 January 2021

Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture

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7 January 2021

Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate

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7 January 2021

Potential treatment of amyotrophic lateral sclerosis with gabapentin: a hypothesis

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7 January 2021

The rat paw formalin test: comparison of noxious agents

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7 January 2021

Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channel

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7 January 2021

Subunit identification and reconstitution of the N-type Ca2+ channel complex purified from brain

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7 January 2021

Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat.

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7 January 2021

Effects of felbamate, gabapentin and lamotrigine on seizure parameters and excitability in the rat hippocampus

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7 January 2021

10.1016/S0920-1211(97)00084-3

Identifiers

DOI

1 reference

8 October 2017

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